52988-34-8 Usage
Description
4'-Methoxybiphenyl-4-carbaldehyde is an organic compound with the molecular formula C14H12O2. It is characterized by its aromatic structure, featuring two phenyl rings connected by a methoxy group and a formyl group. 4'-Methoxybiphenyl-4-carbaldehyde is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Research:
4'-Methoxybiphenyl-4-carbaldehyde is used as a reagent in the development of aryliden-methyloxazolones, which are reversible inhibitors of the Monoacylglycerol Lipase (MAGL) enzyme. These inhibitors have shown promise in cancer treatment, as they can modulate the endocannabinoid system and potentially lead to the suppression of tumor growth and progression.
Used in Chemical Synthesis:
In the chemical industry, 4'-Methoxybiphenyl-4-carbaldehyde can be utilized as a key intermediate in the synthesis of various compounds, such as dyes, pigments, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block for creating novel molecules with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 52988-34-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,8 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 52988-34:
(7*5)+(6*2)+(5*9)+(4*8)+(3*8)+(2*3)+(1*4)=158
158 % 10 = 8
So 52988-34-8 is a valid CAS Registry Number.
52988-34-8Relevant articles and documents
Gold Catalysts Can Generate Nitrone Intermediates from a Nitrosoarene/Alkene Mixture, Enabling Two Distinct Catalytic Reactions: A Nitroso-Activated Cycloheptatriene/Benzylidene Rearrangement
Cheng, Mu-Jeng,Kardile, Rahul Dadabhau,Kuo, Tung-Chun,Liu, Rai-Shung,More, Sayaji Arjun
, p. 5506 - 5511 (2021/07/31)
Gold-catalyzed reactions of cycloheptatrienes with nitrosoarenes yield nitrone derivatives efficiently. This reaction sequence enables us to develop gold-catalyzed aerobic oxidations of cycloheptatrienes to afford benzaldehyde derivatives using CuCl and nitrosoarenes as co-catalysts (10-30 mol %). Our density functional theory calculations support a novel nitroso-activated rearrangement, tropylium → benzylidene. With the same nitrosoarenes, we developed their gold-catalyzed [2 + 2 + 1]-annulations between nitrosobenzene and two enol ethers to yield 5-alkoxyisoxazolidines using 1,4-cyclohexadienes as hydrogen donors.
Nickel-catalyzed cross-coupling of organogold reagents
Hirner, Joshua J.,Blum, Suzanne A.
scheme or table, p. 1299 - 1302 (2011/04/22)
Organogold compounds undergo nickel-catalyzed cross-coupling reactions with aryl and vinyl bromides in high yield under mild conditions. The reaction tolerates both electron-rich and electron-poor organogold complexes, and olefinic bromides undergo cross-coupling with high stereoselectivity. This novel transformation links well-established nickel catalysis with more recent developments in organogold transformations.
