53085-26-0

Basic information

• Product Name: ETHYL 2-AMINO-2-HYDRAZONOACETATE
• Synonyms: Acetic acid, 2-hydrazinyl-2-iMino-, ethyl ester;Ethyl oxalamidrazonate;ETHYL 2-AMINO-2-HYDRAZONOACETATE
• CAS NO: 53085-26-0
• Molecular Formula: C₄H₉N₃O₂
• Molecular Weight: 131.14
• Mol File: 53085-26-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 94-95 °C
• Boiling Point: 186.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• PKA: 3.70±0.10(Predicted)
• CAS DataBase Reference: ETHYL 2-AMINO-2-HYDRAZONOACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-AMINO-2-HYDRAZONOACETATE(53085-26-0)
• EPA Substance Registry System: ETHYL 2-AMINO-2-HYDRAZONOACETATE(53085-26-0)

Safety Data

• Hazardous Substances Data: 53085-26-0(Hazardous Substances Data)

Usage

Uses

Ethyl 2-hydrazinyl-2-iminoacetate is a reactant in the synthesis of triazole derivatives.

Upstream product

• 16982-21-1 ethyl 2-amino-2-thioxoacetate 

Downstream Products

• 74476-38-3 triethyl 1,2,4-triazine-3,5,6-tricarboxylate 
• 35883-52-4 5,6-diphenyl-[1,2,4]triazine-3-carboxylic acid ethyl ester 
• 6498-02-8 ethyl 1,2,4-triazine-3-carboxylate 
• 126421-93-0 Ethyl 6-phenyl-1,2,4-triazine-3-carboxylate 
• 126421-91-8 5-phenyl-[1,2,4]triazine-3-carboxylic acid ethyl ester 
• 112032-61-8 Amino-(benzoyl-hydrazono)-acetic acid ethyl ester; hydrochloride 
• 112032-63-0 Amino-[(4-chloro-benzoyl)-hydrazono]-acetic acid ethyl ester; hydrochloride 
• 112032-62-9 Amino-[(4-methoxy-benzoyl)-hydrazono]-acetic acid ethyl ester; hydrochloride 
• 126421-92-9 Diethyl 6-methyl-1,2,4-triazine-3,5-dicarboxylate 
• 1723-25-7 ethyl 2,3-dioxobutyrate 
• 112032-60-7 Amino-(phenylacetyl-hydrazono)-acetic acid ethyl ester; hydrochloride 
• 141424-42-2 ethyl 5,6-bis(4-methoxyphenyl)-1,2,4-triazine-3-carboxylate 
• 1028832-44-1 ethyl 6-(3-(phenylthio)propyl)-1,2,4-triazine-3-carboxylate 
• 69244-21-9 5-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester 

Relevant articles and documents

Preparation of tetrahydroimidazo[2,1-a]isoquinolines and their use as inhibitors of gastric acid secretion

A series of novel tetrahydroimidazo[2,1-a]isoquinolines was prepared based on a hetero Diels-Alder reaction between an enamine and 1,2,4-triazine as key step. A structure-activity relationship was established focussing on the influence of the substitution

Indole as a Dienophile in Inverse Electron Demand Diels-Alder Reactions: Reactions with 1,2,4-Triazines and 1,2-Diazines

Indole reacts with 1,2,4-triazines in the absence of solvent or in the presence of limited amounts of solvent to produce β- or γ-carbolines, benzonaphthyridines, or the noncyclized 3-indoles.The combined yields of cycloadducts with tricarbalkoxytriazines exceeds 90 percent, with the production of γ-carbolines exceeding 80 percent.The regiochemistry of the adduct and the ratio of the products is determined mainly by electronic effects of the triazine substituents.Indole also ungergoes a cyclocondensation reaction with tetramethyl 1,2-diazine-3,4,5,6-tetracarboxylate to give trimethyl 5H-6-oxophenanthridine-2,3,4-tricarboxylate.