53097-35-1

Basic information

• Product Name: 3-(prop-1-en-2-yl)benzonitrile
• Synonyms: 3-(prop-1-en-2-yl)benzonitrile
• CAS NO: 53097-35-1
• Molecular Weight: 143.188
• Mol File: 53097-35-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(prop-1-en-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(prop-1-en-2-yl)benzonitrile(53097-35-1)
• EPA Substance Registry System: 3-(prop-1-en-2-yl)benzonitrile(53097-35-1)

Safety Data

• Hazardous Substances Data: 53097-35-1(Hazardous Substances Data)

Upstream product

• 40751-59-5 3-isopropyl benzonitrile 
• 6136-68-1 3-acethylbenzonitrile 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 5433-01-2 1-bromo-3-isopropylbenzene 
• 27200-84-6 methyl triphenylphosphonium bromide 

Downstream Products

• 103274-62-0 3-(α-chloro-isopropyl)-benzonitrile 
• 110207-94-8 (3-isopropylphenyl)methanamine 
• 40751-59-5 3-isopropyl benzonitrile 
• 1574520-89-0 3-cyano-α-(bromomethyl)styrene 
• 1156454-41-9 C₁₉H₂₇N₃O 

Relevant articles and documents

Synthesis of 2,5-Diaryl-1,5-dienes from Allylic Bromides Using Visible-Light Photoredox Catalysis

Visible-light photoreductive coupling of 2-arylallyl bromides in the presence of the photocatalyst Ru(bpy)3(PF6)2, a Hantzsch ester, and i-Pr2NEt gives 2,5-diaryl-1,5-dienes in high yield. This method avoids the use of stoichiometric metal reductants and is compatible with the presence of halogen, alkyl, electron-donating, and electron-withdrawing substituents on the aromatic ring.

COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF

The present invention provides novel beta-secretase inhibitors of the general formula (I), where the variables A1, A2, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the claims, a method for their use in treating Alzheimer's disease, and methods for their use in reducing memapsin 2 catalytic activity.