53525-65-8Relevant articles and documents
Imidazo[1,2-a]pyrazine, Imidazo[1,5-a]quinoxaline and?Pyrazolo[1,5-a]quinoxaline derivatives as IKK1 and IKK2 inhibitors
Patinote, Cindy,Bou Karroum, Nour,Moarbess, Georges,Deleuze-Masquefa, Carine,Hadj-Kaddour, Kamel,Cuq, Pierre,Diab-Assaf, Mona,Kassab, Issam,Bonnet, Pierre-Antoine
, p. 909 - 919 (2017/07/27)
The transcription nuclear factor NF-κB plays a pivotal role in chronic and acute inflammatory diseases. Among the several and diverse strategies for inhibiting NF-κB, one of the most effective approach considered by the pharmaceutical industry seems to be
DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR
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Page 81-82, (2010/02/07)
A difluoroalkene derivative which is sufficiently effective in controlling various pests even when used in a small dose and is highly safe for crops, natural enemies to the pests, and animals; and an intermediate for the derivative. The difluoroalkene derivative is represented by the general formula: [I] wherein L1 and L2 are the same or different and each represents oxygen or sulfur; n is an integer of 2 to 8; and Q represents a 5- to 12-membered heterocyclic group having any desired heteroatom selected among nitrogen, oxygen, and sulfur.
Synthesis of imidazo[1,5-a]quinoxalin-4(5H)-one template via a novel intramolecular cyclization process
Norris, Derek,Chen, Ping,Barrish, Joel C.,Das, Jagabandhu,Moquin, Robert,Chen, Bang-Chi,Guo, Peng
, p. 4297 - 4299 (2007/10/03)
A novel, efficient, and regiospecific method for the construction of the imidazo[1,5-a]quinoxalin-4(5H)-one template is described. The key reaction involves an intramolecular cyclization process and provides the desired products in excellent yield.