53958-94-4

Basic information

• Product Name: 3-(1H-Imidazol-4-yl)-propionic acid methyl ester hydrochloride
• Synonyms: 3-(1H-Imidazol-4-yl)-propionic acid methyl ester hydrochloride;methyl 3-(1H-imidazol-5-yl)propanoate hydrochloride;methyl 3-(1H-imidazo-5-yl)propanoate hydrochloride;METHYL 3-(1H-IMIDAZOL-4-YL)PROPANOATE HCL
• CAS NO: 53958-94-4
• Molecular Formula: C₇H₁₀N₂O₂*ClH
• Molecular Weight: 190.62744
• Mol File: 53958-94-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-(1H-Imidazol-4-yl)-propionic acid methyl ester hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-Imidazol-4-yl)-propionic acid methyl ester hydrochloride(53958-94-4)
• EPA Substance Registry System: 3-(1H-Imidazol-4-yl)-propionic acid methyl ester hydrochloride(53958-94-4)

Safety Data

• Hazardous Substances Data: 53958-94-4(Hazardous Substances Data)

Upstream product

• 54260-89-8 trans-4-imidazoleacrylic acid methyl ester hydrochloride 
• 67-56-1 methanol 
• 53958-93-3 3-(4-imidazolyl)propionic acid monohydrochloride 
• 3465-72-3 urocanic Acid 
• 1074-59-5 3-(imidazol-4-yl)propionic acid 
• 104-98-3 urocanic acid 

Downstream Products

• 102676-60-8 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester 
• 160446-35-5 3-(1H-1-triphenylmethylimidazol-4-yl)propanoic acid 
• 637337-52-1 (R)-4-(1-methylethyl)-5,5-diphenyl-3-{3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoyl}oxazolidin-2-one 
• 637337-70-3 (S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid 
• 847153-59-7 H-(S)-β²hHis(Tr)-OH 
• 847153-57-5 (S)-benzyl 2-(hydroxymethyl)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoate 
• 847153-58-6 (S)-benzyl 2-(azidomethyl)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoate 
• 847153-53-1 (4R)-3-{2-(azidomethyl)-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoyl}-4-(1-methylethyl)-5,5-diphenyloxazolidin-2-one 
• 152030-49-4 3-(1-trityl-1H-imidazol-4-yl)propan-1-ol 
• 183155-66-0 3-<1-(triphenylmethyl)imidazol-4(5)-yl>propyl 4-bromobenzyl ether 
• 183155-67-1 3-<1-(triphenylmethyl)imidazol-4(5)-yl>propyl 4-iodobenzyl ether 
• 174583-07-4 Bromoproxyfan 
• 152028-96-1 iodoproxyfan 

Relevant articles and documents

3,4,5-TRISUBSTITUTED-1,2,4-TRIAZOLES AND 3,4,5-TRISUBSTITUTED-3-THIO-1,2,4-TRIAZOLES AND USES THEREOF

The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists.

Organic compounds

The present invention provides a compound of formula I: Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase or aromatase. Accordingly, the compound of formula I can be used in treatment of hypokalemia, hypertension, congestive heart failure, atrial fibrillation, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome X, obesity, nephropathy, post-myocardial infarction, coronary heart diseases, inflammation, increased formation of collagen, fibrosis such as cardiac or myocardiac fibrosis and remodeling following hypertension and endothelial dysfunction, gynecomastia, osteoporosis, prostate cancer, endometriosis, uterine fibroids, dysfunctional uterine bleeding, endometrial hyperplasia, polycystic ovarian disease, infertility, fibrocystic breast disease, breast cancer and fibrocystic mastopathy. Finally, the present invention also provides a pharmaceutical composition.

Inhibitors of prenyl-protein transferase

The present invention is directed to macrocyclic compounds which inhibit prenyl-protein transferase (FTase) and the prenylation of the oncogene protein Ras. The invention is further directed to chemothera-peutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.