54166-79-9

Basic information

• Product Name: Acetic acid, [[2-nitro-4-(trifluoromethyl)phenyl]amino]oxo-, ethyl ester
• CAS NO: 54166-79-9
• Molecular Formula: C11H9F3N2O5
• Molecular Weight: 306.198
• Mol File: 54166-79-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Acetic acid, [[2-nitro-4-(trifluoromethyl)phenyl]amino]oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [[2-nitro-4-(trifluoromethyl)phenyl]amino]oxo-, ethyl ester(54166-79-9)
• EPA Substance Registry System: Acetic acid, [[2-nitro-4-(trifluoromethyl)phenyl]amino]oxo-, ethyl ester(54166-79-9)

Safety Data

• Hazardous Substances Data: 54166-79-9(Hazardous Substances Data)

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 4755-77-5 Ethyl oxalyl chloride 
• 400-98-6 4-trifluoromethyl-2-nitroaniline 

Downstream Products

• 55687-31-5 Lilly 72525 

Relevant articles and documents

Pyrrolyl quinoxalindiones their production and use as AMPA receptor antagonists

Pyrrolylquinoxalinediones of the formula I and their tautomeric and isomeric forms, and their physiologically tolerated salts are described, where the variables have the following meaning: R1hydrogen, C1-C6-alkyl, substitu

Pyrrolylquinoxalinediones: A new class of AMPA receptor antagonists

Pyrrolylquinoxalinediones were synthesized and their affinities for the AMPA receptor were determined. Most compounds showed moderate to good affinities. The acetic acid derivative 8b exhibited a K(i) value of 70 nM and was equipotent to NBQX 1. Structure activity relationships are discussed. Selected compounds were tested for their potency to inhibit AMPA induced lethal convulsions in mice. In this in vivo model the compounds showed improved potency compared with NBQX.

Antisecretory oxamic acid esters

Variously substituted oxanilic acid esters possessing anti-secretary activity are useful anti-ulcer agents.