5435-06-3

Basic information

• Product Name: 4-methyl-N-(4-phenylbutyl)benzenesulfonamide
• Synonyms: benzenesulfonamide, 4-methyl-N-(4-phenylbutyl)-
• CAS NO: 5435-06-3
• Molecular Formula: C₁₇H₂₁NO₂S
• Molecular Weight: 303.4191
• Mol File: 5435-06-3.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 463.6°C at 760 mmHg
• Flash Point: 234.2°C
• Density: 1.138g/cm³
• Vapor Pressure: 8.95E-09mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 4-methyl-N-(4-phenylbutyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(4-phenylbutyl)benzenesulfonamide(5435-06-3)
• EPA Substance Registry System: 4-methyl-N-(4-phenylbutyl)benzenesulfonamide(5435-06-3)

Safety Data

• Hazardous Substances Data: 5435-06-3(Hazardous Substances Data)

Upstream product

• 13214-66-9 4-phenyl-1-butylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7332-01-6 1-(4-azidobutyl)benzene 
• 182324-83-0 4-methyl-N-(4-phenylbut-3-yn-1-yl)benzenesulfonamide 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 830319-71-6 2,3-dihydropyrrolo[1,2-b][1,2]benzisothiazole-5,5-dioxide 
• 830319-72-7 1,2,3,9b-tetrahydropyrrolo[1,2-b][1,2]benzisothiazole-5,5-dioxide 
• 830319-69-2 1-(2-bromobenzenesulfonyl)-2,3-dihydro-1H-pyrrole 
• 830319-67-0 1-(2-bromobenzenesulfonyl)pyrrolidin-2-one 
• 830319-68-1 1-(2-bromobenzenesulfonyl)pyrrolidin-2-ol 
• 2046-18-6 4-phenylbutyronitrile 
• 300-57-2 allylbenzene 
• 201230-82-2 carbon monoxide 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 5435-07-4 N-methyl-N-(4-phenyl-butyl)-toluene-4-sulfonamide 
• 24517-59-7 2-phenyl-1-(4-methylbenzenesulfonyl)pyrrolidine 
• 18328-11-5 3-benzyl propionaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 374590-35-9 4-(4-iodophenyl)butyraldehyde 
• 4265-99-0 N-methyl-4-phenylbutylamine 
• 1332887-41-8 1-phenyl-4-tosylamidobutyl nitrate 

Relevant articles and documents

Nickel/Photoredox Dual Catalytic Cross-Coupling of Alkyl and Amidyl Radicals to Construct C(sp3)-N Bonds

The construction of C(sp3)-N bonds via direct radical-radical cross-coupling under benign conditions is a desirable but challenging approach. Herein, the cross-coupling of alkyl and amidyl radicals to build aliphatic C-N bonds in a concise, mild, and oxid

Direct Synthesis of α-Amino Nitriles from Sulfonamides via Base-Mediated C-H Cyanation

Herein, we disclose a transition-metal-free reaction system that enables α-cyanation of sulfonamides through C-H bond cleavage for the preparation of α-amino nitriles, including difficult-to-access all-alkyl α-tertiary scaffolds. More than 50 substrate examples prove a wide functional group tolerance. Additionally, its synthetic practicality is highlighted by gram-scalability and the late-stage modification of natural compounds. Mechanistic experiments suggest that this process involves in situ formation of an imine intermediate via base-promoted elimination of HF.

Chiral Piperidines from Acyclic Amines via Enantioselective, Radical-Mediated δ C–H Cyanation

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