54370-01-3

Basic information

• Product Name: 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene
• Synonyms: Toluene,2-bromo-a-chloro-4,5-dimethoxy- (7CI);Veratrole, 4-bromo-5-(chloromethyl)- (6CI); 1-Bromo-2-chloromethyl-4,5-dimethoxybenzene;2-Bromo-4,5-dimethoxybenzyl chloride; 6-Bromo-3,4-dimethoxybenzyl chloride
• CAS NO: 54370-01-3
• Molecular Formula: C₉H₁₀BrClO₂
• Molecular Weight: 265.54
• Mol File: 54370-01-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 309.5°C at 760 mmHg
• Flash Point: 141°C
• Appearance: /
• Density: 1.464g/cm³
• Vapor Pressure: 0.00116mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene(54370-01-3)
• EPA Substance Registry System: 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene(54370-01-3)

Safety Data

• Hazardous Substances Data: 54370-01-3(Hazardous Substances Data)

Usage

Appearance

White to off-white solid describes the physical form and color of the compound, which may vary slightly in shade.

Solubility

Insoluble in water, soluble in organic solvents refers to the compound's ability (or inability) to dissolve in different types of solvents, which can impact its applications and handling.

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals indicates the compound's role as a precursor or building block in the production of various drugs and chemicals used in agriculture.

Reactivity

Possesses both bromine and chlorine atoms highlights the presence of these reactive halogens in the compound, which can participate in various chemical reactions and make it a versatile building block for creating other organic compounds.

Aromatic structure

A valuable compound for the development of new drugs and chemical products refers to the compound's aromatic nature, which can contribute to its stability and potential applications in medicinal chemistry and other fields.

Safety

Handle with care and follow proper safety protocols due to potential reactivity and toxicity emphasizes the importance of taking necessary precautions when working with this compound to minimize risks associated with its potential hazards.

InChI:InChI=1/C9H10BrClO2/c1-12-8-3-6(5-11)7(10)4-9(8)13-2/h3-4H,5H2,1-2H3

Upstream product

• 50-00-0 formaldehyd 
• 2859-78-1 4-Bromoveratrole 
• 54370-00-2 2-bromo-4,5-dimethoxybenzyl alcohol 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 51655-39-1 2-bromo-4,5-dimethoxyphenylacetonitrile 
• 122323-02-8 2-(2-Bromo-4,5-dimethoxy-phenyl)-1-(2,3-dimethoxy-phenyl)-ethanone 
• 112378-02-6 8-benzyloxy-N-benzoyl-1-(2'-bromo-4',5'-dimethoxybenzyl)-1,2-dihydro-7-methoxyisoquinoline-1-carbonitrile 
• 52783-79-6 Diethyl-(2-brom-4.5-dimethoxy)-benzylacetamidomalonat 
• 859942-25-9 1,2-bis(2-bromo-4,5-dimethoxyphenyl)ethane 
• 299215-69-3 (E)-1,2-bis(2-bromo-4,5-dimethoxyphenyl)-N,N-dimethylethenylamine 
• 952196-37-1 1-(2-bromo-4,5-dimethoxybenzyl)-7,8-dimethoxy-3-methyl-1,2,4,5-tetrahydro-3H-3-benzazepin-2-one 
• 2292-20-8 Muramin 
• 656807-26-0 2-ethenyl-4,5-dimethoxybenzeneacetonitrile 
• 656807-33-9 2-ethenyl-4,5-dimethoxy-N-2-propenyl-benzeneethanamine 
• 656807-35-1 2-ethenyl-4,5-dimethoxy-N-3-butenyl-benzeneethanamine 
• 96756-82-0 2-bromo-4,5-dimethoxybenzyl 2-bromo-4,5-dimethoxyphenyl ketone 
• 299216-00-5 4,5-bis(2-bromo-4,5-dimethoxyphenyl)isoxazole 
• 5963-51-9 1,2-bis(3,4-dimethoxyphenyl)ethane 

Relevant articles and documents

NOVEL 6,7-DIHYDROPYRIDO[2,1-A]PHTHALAZIN-2-ONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula: wherein R1 to R6 are as described herein, compositions including the compounds and methods of using the compounds.

2,3-DIHYDRO-1H-ISOINDOL-1-IMINE DERIVATIVES USEFUL AS THROMBIN PAR-1 RECEPTOR ANTAGONIST

The present invention is directed to novel 2,3-dihydro-1H-isoindol-1-imine derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the thrombin PAR-1 receptor antagonists.

TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP

The present invention relates to a compound of the general formula (1): (1)wherein, Y is a methylene group, and the like; A is an optionally substituted heterocyclic group, and the like; B is an optionally substituted phenyl group, and the like; R1 is an optionally substituted alkyl group, and the like; and R2 is an optionally substituted amino group, and the like; or a pharmaceutically acceptable derivative thereof, which has an inhibitory activity against cholesteryl ester transfer protein (CETP), thereby being useful for prophylaxis and/or treatment of arteriosclerotic diseases, hyperlipemia or dyslipidemia, and the like.