5441-99-6 Usage
Description
N,N-Diethyl methacrylamide, also known as N,N-dimethylacrylamide, is a monomer with a hydrophobic group (methyl and ethyl groups) that is commonly polymerized to form temperature-sensitive hydrogels. Post-polymerization, these gels exhibit temperature sensitivity due to their lower critical solution temperature (LCST). This property makes them suitable for various applications, particularly in the field of drug delivery systems.
Uses
Used in Drug Delivery Systems:
N,N-Diethyl methacrylamide is used as a monomer for the development of temperature-sensitive hydrogels. The reason for its application is that the lower critical solution temperature (LCST) of the resulting polymer is around body temperature, which allows for the sol-gel phase conversion at body temperature. This property is beneficial for the controlled release of drugs and enhances the efficiency of drug delivery.
Used in Biomedical Applications:
In the biomedical industry, N,N-diethyl methacrylamide is used as a key component in the synthesis of hydrogels for various applications, such as tissue engineering, wound healing, and controlled drug release. The temperature sensitivity of the resulting hydrogels allows for precise control over the release of bioactive molecules, making it an ideal material for targeted drug delivery and tissue regeneration.
Used in Research and Development:
In the field of polymer science and materials research, N,N-diethyl methacrylamide is used as a model compound to study the effects of hydrophobic groups on the temperature sensitivity of polymers. This knowledge can be applied to the design and development of new temperature-sensitive materials with potential applications in various industries, including pharmaceuticals, agriculture, and environmental management.
Check Digit Verification of cas no
The CAS Registry Mumber 5441-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5441-99:
(6*5)+(5*4)+(4*4)+(3*1)+(2*9)+(1*9)=96
96 % 10 = 6
So 5441-99-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO/c1-5-9(6-2)8(10)7(3)4/h3,5-6H2,1-2,4H3
5441-99-6Relevant articles and documents
N-alkylation of methacrylamide with alkyl halides
Shirshin,Kazantsev,Kazakov,Danov
, p. 1418 - 1420 (2007/10/03)
N-Alkylation of methacrylamide with ethyl bromide, ethyl iodide, and allyl bromide in acetonitrile in the presence of alkalis yields N- and N,N-substituted methacrylamides. The effect of temperature, reactant ratio, nature of the alkyl halide, and water content on the reaction course was studied.
