5444-81-5

Basic information

• Product Name: 6-chloro-9-cyclopentyl-9H-purine
• Synonyms: 6-chloro-9-cyclopentyl-9H-purine
• CAS NO: 5444-81-5
• Molecular Formula: C₁₀H₁₁ClN₄
• Molecular Weight: 222.67414
• Mol File: 5444-81-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 392.6°C at 760 mmHg
• Flash Point: 191.2°C
• Appearance: /
• Density: 1.56g/cm³
• Vapor Pressure: 2.27E-06mmHg at 25°C
• Refractive Index: 1.762
• CAS DataBase Reference: 6-chloro-9-cyclopentyl-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-9-cyclopentyl-9H-purine(5444-81-5)
• EPA Substance Registry System: 6-chloro-9-cyclopentyl-9H-purine(5444-81-5)

Safety Data

• Hazardous Substances Data: 5444-81-5(Hazardous Substances Data)

Usage

Structure

A derivative of purine

Functional Groups

Chlorine (Cl) at the 6th position
Cyclopentyl group at the 9th carbon

Biological Activity

Inhibitor of enzymes such as phosphodiesterase
Antagonist of adenosine receptors

Utility

Used in research and pharmaceutical applications

Importance

Potential pharmacological properties
Aid in the development of new drugs and treatments

InChI:InChI=1/C10H11ClN4/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-7/h5-7H,1-4H2

Upstream product

• 96-41-3 Cyclopentanol 
• 87-42-3 6-chloropurine 
• 5452-43-7 5-amino-4-chloro-6-(N-cyclopentylamino)pyrimidine 
• 122-51-0 orthoformic acid triethyl ester 
• 1003-03-8 Cyclopentamine 
• 137-43-9 Cyclopentyl bromide 

Downstream Products

• 715-91-3 9-cyclopentyladenine 
• 35966-95-1 9-cyclopentyl-N⁶-benzyladenine 
• 1145671-91-5 6-(2,4-dimethoxybenzyl)amino-9-cyclopentyl-9H-purine 
• 1145671-85-7 6-[2-(phenylamino)ethyl]amino-9-cyclopentyl-9H-purine 
• 1145671-90-4 6-(4-methoxybenzyl)amino-9-cyclopentyl-9H-purine 
• 1383484-00-1 9-benzyl-6,8-dicyclopentyl-9H-purine 
• 1510826-44-4 N,N-dibenzyl-2-(9-cyclopentyl-9H-purin-6-yl)-4-phenylbutanamide 

Relevant articles and documents

Regioselective alkylation reaction of purines under microwave irradiation

The alkylation of purines which is generally carried out after anion formation by treatment with a base and alkyl halide is complicated and in the best cases, mixtures of N-alkylated compounds are obtained. Purine derivatives can be acquired from alkylati

Synthesis and antimicrobial evaluation of some new substituted purine derivatives

A series of 8,9-disubstituted adenines (4, 5, 8), 6-substituted aminopurines (10-13) and 9-(p-fluorobenzyl/cyclopentyl)-6-substituted aminopurines (16, 17, 19-30) have been prepared and the antimicrobial activities of these compounds against Staphylococcu

Mitsunobu reactions for the synthesis of carbocyclic analogues of nucleosides: Examintion of the regioselectivity

In order to provide a general synthetic method for carbocyclic nucleosides, regioselectivities in Mitsunobu reaction of purine, pyrimidin-2-one and their substituted derivatives with a variety of alcohols with a variety of alcohols were examined and found to depend upon both substituents of the bases and kind of the alcohols.