54551-50-7

Basic information

• Product Name: Benzoyl chloride, 2-(acetyloxy)-4-chloro-
• CAS NO: 54551-50-7
• Molecular Formula: C9H6Cl2O3
• Molecular Weight: 233.051
• Mol File: 54551-50-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-(acetyloxy)-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-(acetyloxy)-4-chloro-(54551-50-7)
• EPA Substance Registry System: Benzoyl chloride, 2-(acetyloxy)-4-chloro-(54551-50-7)

Safety Data

• Hazardous Substances Data: 54551-50-7(Hazardous Substances Data)

Upstream product

• 5106-98-9 4-chlorosalicylic acid 
• 17336-08-2 2-carboxy-5-chlorophenyl acetate 

Downstream Products

• 1415566-82-3 C₁₂H₈ClN₃O₅S 
• 1148-48-7 7-chloro-2-phenyl-4H-1-benzopyran-4-one 
• 1403475-74-0 1-(2-acetoxy-4-chlorophenyl)-3-phenyl-2-propyn-1-one 
• 1237518-81-8 tert-butyl 2-(2-acetoxy-4-chlorobenzamido)-4-phenylbenzoate 
• 1237514-37-2 2-(4-chloro-2-hydroxybenzamido)-4-phenylbenzoic acid 
• 1237518-82-9 tert-butyl 2-(4-chloro-2-hydroxybenzamido)-4-phenylbenzoate 
• 66508-45-0 monoammonium salt of 3-[N-(4-chloro-2-hydroxy benzoyl)-N-hydroxyamino]propylphosphonic acid 
• 54551-41-6 N-butoxy-4-chloro-2-hydroxy-benzamide 
• 54551-39-2 4-chloro-2-hydroxy-N-methoxy-benzamide 

Relevant articles and documents

Synthesis and antioxidant activities of berberine 9-: O -benzoic acid derivatives

Although berberine (BBR) shows antioxidant activity, its activity is limited. We synthesized 9-O-benzoic acid berberine derivatives, and their antioxidant activities were screened via ABTS, DPPH, HOSC and FRAP assays. The para-position was modified with halogen elements on the benzoic acid ring, which led to an enhanced antioxidant activity and the substituent on the ortho-position was found to be better than the meta-position. Compounds 8p, 8c, 8d, 8i, 8j, 8l, and especially 8p showed significantly higher antioxidant activities, which could be attributed to the electronic donating groups. All the berberine derivatives possessed proper lipophilicities. In conclusion, compound 8p is a promising antioxidant candidate with remarkable elevated antioxidant activity and moderate lipophilicity.

Synthesis of flavones and γ-benzopyranones using mild sonogashira coupling and 18-crown-6 ether mediated 6-endo cyclization

An efficient method for the synthesis of flavones and γ- benzopyranones has been developed utilizing a mild Sonogashira coupling and 18-crown-6 ether mediated 6-endo cyclization of o-alkynoylphenyl acetates. By using this strategy, flavones and γ-benzopyranones bearing electron-donating groups, halogens, and simple alkyl substituents were synthesized in satisfactory yields. A facile, mild, and selective method for the synthesis of flavones and γ-benzopyranones is reported. o-Alkynoylphenyl acetates were obtained from either acyl chloride derivatives or substituted salicylates. Upon removing the acetate group, flavones and γ- benzopyranones were synthesized within 15 min with the aid of 18-crown-6 ether. A library of flavones and γ-benzopyranones was established. Copyright

N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An N-acyl anthranilic acid derivative represented by general formula (1) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl group or th