548472-48-6

Basic information

• Product Name: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride
• Synonyms: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride;4-Methoxy-2-(1-methylethoxy)benzenecarboximidic acid ethyl ester hydrochloride;2-Isopropoxy-4-methoxy-benzimidic acid ethyl ester hydrochloride;ETHYL 2-ISOPROPOXY-4-METHOXYBENZIMIDATE HCL;thyl 2-isopropoxy-4-methoxybenzimidate hydrochloride
• CAS NO: 548472-48-6
• Molecular Formula: C₁₃H₁₉NO₃*ClH
• Molecular Weight: 0
• Mol File: 548472-48-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 352.1°C at 760 mmHg
• Flash Point: 166.7°C
• Appearance: /
• Vapor Pressure: 2.76E-05mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride(548472-48-6)
• EPA Substance Registry System: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride(548472-48-6)

Safety Data

• Hazardous Substances Data: 548472-48-6(Hazardous Substances Data)

Usage

General Description

Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride is a chemical compound with the molecular formula C13H19ClN2O3. It is a white to off-white crystalline powder that is soluble in organic solvents such as methanol and ethanol. Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride is a derivative of benzimidazole and is commonly used in organic synthesis as a reagent for the preparation of various pharmaceutical and agricultural chemicals. It is also used as a building block in the synthesis of novel heterocyclic compounds. Additionally, ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride has potential applications in the pharmaceutical industry for the development of new drugs and therapeutic agents.

InChI:InChI=1/C13H19NO3.ClH/c1-5-16-13(14)11-7-6-10(15-4)8-12(11)17-9(2)3;/h6-9,14H,5H2,1-4H3;1H

Upstream product

• 548472-47-5 2-isopropoxy-4-methoxy-benzonitrile 
• 64-17-5 ethanol 

Downstream Products

• 844692-35-9 trans-4,5-Bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole 

Relevant articles and documents

Substituted Dihydroimidazoles and their Use in the Treatment of Tumors

The invention relates to dihydroimidazoles of formula rac-(I), wherein the radicals and symbols are as defined herein; their use as inhibitors of the interaction of the MDM2 protein with a p53-like peptide, new pharmaceutical formulations comprising said compounds, said compounds for use in the therapeutic treatment of warm-blooded animals, especially humans, their use in the treatment of proliferative diseases or for the manufacture of pharmaceutical formulations useful in the treatment of proliferative diseases that respond to modulation of the interaction of the MDM2 protein with a p53-like peptide, a pharmaceutical formulation e.g. useful in the treatment of proliferative diseases that respond to modulation of the interaction of the MDM2 protein with a p53-like peptide comprising said compound, methods of treatment comprising administration of said compounds to a warm-blooded animal, and/or processes for the manufacture of said compounds.

Cis-imidazolines

The present invention provides compounds according to formula I and formula II and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity