549501-27-1Relevant articles and documents
Structure-activity relationships for antibacterial to antifungal conversion of kanamycin to amphiphilic analogues
Fosso, Marina,AlFindee, Madher N.,Zhang, Qian,Nziko, Vincent De Paul Nzuwah,Kawasaki, Yukie,Shrestha, Sanjib K.,Bearss, Jeremiah,Gregory, Rylee,Takemoto, Jon Y.,Chang, Cheng-Wei Tom
, p. 4398 - 4411 (2015/05/13)
Novel fungicides are urgently needed. It was recently reported that the attachment of an octyl group at the O-4″ position of kanamycin B converts this antibacterial aminoglycoside into a novel antifungal agent. To elucidate the structure-activity relation
AMINOGLYCOSIDE ANTIBIOTICS AND METHODS OF USING SAME
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Page 31-34, (2008/06/13)
The present invention relates to aminoglycoside compounds having antibiotic activity. Moreover, the present invention relates to L-aminoglycoside compounds and diastereomers thereof which posses antibiotic activity and are not susceptible to development of resistant bacterial strains. The present invention also relates to methods of treatment and pharmaceutical compositions that utilize or comprise one or more of aminoglycoside compounds provided by the invention.