551929-85-2

Basic information

• Product Name: (2S,4S)-4-Azido-1-{(2S,3R)-2-[(S)-4-[3-(2-benzyloxycarbonylamino-acetylamino)-4-hydroxy-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyrylamino]-3-hydroxy-butyryl}-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 551929-85-2
• Molecular Weight: 876.923
• Mol File: 551929-85-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-Azido-1-{(2S,3R)-2-[(S)-4-[3-(2-benzyloxycarbonylamino-acetylamino)-4-hydroxy-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyrylamino]-3-hydroxy-butyryl}-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-Azido-1-{(2S,3R)-2-[(S)-4-[3-(2-benzyloxycarbonylamino-acetylamino)-4-hydroxy-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyrylamino]-3-hydroxy-butyryl}-pyrrolidine-2-carboxylic acid methyl ester(551929-85-2)
• EPA Substance Registry System: (2S,4S)-4-Azido-1-{(2S,3R)-2-[(S)-4-[3-(2-benzyloxycarbonylamino-acetylamino)-4-hydroxy-phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyrylamino]-3-hydroxy-butyryl}-pyrrolidine-2-carboxylic acid methyl ester(551929-85-2)

Safety Data

• Hazardous Substances Data: 551929-85-2(Hazardous Substances Data)

Upstream product

• 642408-91-1 2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(4-hydroxy-3-nitro-phenyl)-butyric acid 
• 642408-92-2 (S)-4-(3-Chloro-4-methoxy-phenyl)-2-(3-methyl-ureido)-4-oxo-butyric acid 
• 198560-10-0 Fmoc-hTyrOH 
• 296774-96-4 BocThrAzpOMe 
• 84520-67-2 (2S,4R)-4-(methylsulfonyloxy)pyrrolidine-1,2-dicarboxylic acid 1-tert-butylester-2-methylester 
• 84520-68-3 N-tert-butoxycarbonyl-cis-4-azido-L-proline methyl ester 
• 84520-69-4 methyl (2S,4S)-4-azidopyrrolidine-2-carboxylate 
• 221243-01-2 (S)-homotyrosine 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 1499-56-5 (R)-4-hydroxy-L-proline ethyl ester 
• 766-51-8 2-Chloroanisole 
• 2899-60-7 Cbz-Gly-ONSuc 
• 772327-98-7 (2S,4S)-1-((2S,3R)-2-Amino-3-hydroxy-butyryl)-4-azido-pyrrolidine-2-carboxylic acid methyl ester 

Downstream Products

• 551929-86-3 [26-azido-6-{2-[3-(2-benzyloxycarbonylamino-acetylamino)-4-hydroxy-phenyl]-ethyl}-11-hydroxy-3,15-bis-(1-hydroxy-ethyl)-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaaza-tricyclo[22.3.0.0^9,13]heptacos-18-yl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Discovery, SAR, synthesis, pharmacokinetic and biochemical characterization of A-192411: A novel fungicidal lipopeptide-(I)

The echinocandin class of cyclic lipopepetides has been simplified to discover potent antifungal compounds. Namely A-192411 shows good in vitro activity against common pathogenic yeasts and has an acceptable safety window in vivo. Discovery, limited SAR, synthesis, biochemical and pharmaco-dynamic profiles of A-192411 are presented.