5531-95-3

Basic information

• Product Name: (-)-Argemonine
• Synonyms: (-)-Argemonine;(5S,11S)-5,6,11,12-Tetrahydro-2,3,8,9-tetramethoxy-13-methyl-5,11-epiminodibenzo[a,e]cyclooctene;[5S,11S,(-)]-5,6,11,12-Tetrahydro-2,3,8,9-tetramethoxy-13-methyl-5,11-epiminodibenzo[a,e]cyclooctene;Nsc148821
• CAS NO: 5531-95-3
• Molecular Formula: C₂₁H₂₅NO₄
• Molecular Weight: 355.4275
• Mol File: 5531-95-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 132 °C
• Boiling Point: 446°C at 760 mmHg
• Flash Point: 125.2°C
• Appearance: /
• Density: 1.156g/cm³
• Vapor Pressure: 3.76E-08mmHg at 25°C
• Refractive Index: 1.568
• PKA: 6.55±0.20(Predicted)
• CAS DataBase Reference: (-)-Argemonine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-Argemonine(5531-95-3)
• EPA Substance Registry System: (-)-Argemonine(5531-95-3)

Safety Data

• Hazardous Substances Data: 5531-95-3(Hazardous Substances Data)

Usage

Uses

(-)-Argemonine is a pavine alkaloid that has shown some cytotoxic and anti-HIV activity.

InChI:InChI=1/C21H25NO4/c1-22-16-6-12-8-18(23-2)20(25-4)10-14(12)17(22)7-13-9-19(24-3)21(26-5)11-15(13)16/h8-11,16-17H,6-7H2,1-5H3

Upstream product

• 2246-26-6 1,2-dihydro-2-methylpapaverine 
• 50-00-0 formaldehyd 
• 64-18-6 formic acid 
• 5703-21-9 3,4-dimethoxyphenylacetaldehyde 
• 177963-88-1 N,N-Bis-[2-(3,4-dimethoxy-phenyl)-1-trimethylsilanyloxy-ethyl]-formamide 
• 7306-46-9 4-chloromethyl-1,2-dimethoxy-benzene 

Downstream Products

• 17482-72-3 4',5',4'',5''-Tetramethoxy-7-benzylmethyl-amino-dibenzo<1.2,5.6>cyclooctatrien-(1,3,5) 
• 17482-72-3 (+/-)-N-Benzyl-pavinmethin 

Relevant articles and documents

Extremely facile formation of the pavine alkaloid skeleton by the photoreaction between isoquinoline and benzyltrifluoroborate

Appling the photo-benzylation of isoquinoline with benzyltrifluoroborate, an extremely facile method for the construction of a pavine alkaloid skeleton was developed. When 3-methoxybenzylboron reagents were employed to the reaction, it was found that not

Synthesis and reactions of N,N-bis[1-(trimethylsiloxy)alkyl]-formamides: Preparation of (±)-argemonine and (±)-norargemonine

Symmetrical and unsymmetrical N,N-bis[1-(trimethylsiloxy)alkyl]formamides are prepared and their reactions investigated, including an application to the synthesis of the pavine alkaloids (±)-argemonine and (±)-norargemonine.