5533-02-8

Basic information

• Product Name: Benzoic acid, 3-methoxy-4-(methoxymethoxy)-
• CAS NO: 5533-02-8
• Molecular Formula: C10H12O5
• Molecular Weight: 212.202
• Mol File: 5533-02-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 155-156 °C(Solv: benzene (71-43-2); ethyl ether (60-29-7))
• Boiling Point: 343.1±32.0 °C(Predicted)
• Density: 1.227±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 3-methoxy-4-(methoxymethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-methoxy-4-(methoxymethoxy)-(5533-02-8)
• EPA Substance Registry System: Benzoic acid, 3-methoxy-4-(methoxymethoxy)-(5533-02-8)

Safety Data

• Hazardous Substances Data: 5533-02-8(Hazardous Substances Data)

Upstream product

• 617-05-0 ethyl vanillate 
• 5942-32-5 ethyl 3-methoxy-4-(methoxymethoxy)benzoate 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 107-30-2 chloromethyl methyl ether 
• 350802-94-7 3-methoxy-4-methoxymethoxy-benzoic acid methoxymethyl ester 
• 5533-00-6 3-methoxy-4-methoxymethoxy-benzaldehyde 

Downstream Products

• 1161720-14-4 N,N-diethyl-3-methoxy-4-(methoxymethoxy)benzamide 
• 350802-99-2 N-(2-hydroxy-ethyl)-3-methoxy-N-(4-methoxy-benzyloxy)-4-methoxymethoxy-benzamide 
• 350802-98-1 3-methoxy-N-(4-methoxy-benzyloxy)-4-methoxymethoxy-benzamide 
• 350803-24-6 (S)-3-Hydroxy-2-(3-methoxy-4-methoxymethoxy-benzoylamino)-propionic acid methyl ester 
• 350803-30-4 (R)-3-Hydroxy-2-(3-methoxy-4-methoxymethoxy-benzoylamino)-propionic acid methyl ester 
• 350803-31-5 (R)-2-(3-Methoxy-4-methoxymethoxy-phenyl)-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Phosphoramidite containing phenolic hydroxyl, preparation method and application of phosphoramidite

The invention provides phosphoramidite containing phenolic hydroxyl and a preparation method and application of the phosphoramidite. Specifically, the invention discloses a compound shown as a formulaI, a preparation method of the compound and application of the compound serving as a solid synthesis unit. By utilizing the compound as shown in the formula I, radionuclide can be simply and efficiently labeled on nucleic acids such as aptamers, siRNAs or mRNAs, so that diagnostic reagents and therapeutic drugs are prepared.

Vanilloid and isovanilloid analogues as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases

As aminoacyl adenylate surrogates, a series of methionyl and isoleucyl phenolic analogues containing bioisosteric linkers mimicking ribose have been investigated. Inhibition of synthesized compounds to the aminoacylation reaction by the corresponding Escherichia coli methionyl-tRNA and isoleucyl-tRNA synthetases indicated that 18 was found to be a potent inhibitor of isoleucyl-tRNA synthetase. A molecular modeling study demonstrated that in 18, isovanillate and hydroxamate served as proper surrogates for adenine and ribose in isoleucyl adenylate, respectively.