55359-68-7

Basic information

• Product Name: Benzaldehyde, 2-(methoxymethoxy)-5-methyl-
• CAS NO: 55359-68-7
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 55359-68-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-(methoxymethoxy)-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-(methoxymethoxy)-5-methyl-(55359-68-7)
• EPA Substance Registry System: Benzaldehyde, 2-(methoxymethoxy)-5-methyl-(55359-68-7)

Safety Data

• Hazardous Substances Data: 55359-68-7(Hazardous Substances Data)

Upstream product

• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 107-30-2 chloromethyl methyl ether 
• 106-44-5 p-cresol 
• 25458-49-5 1-(methoxymethoxy)-4-methylbenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 115560-39-9 3-Hydroxy-3-(2-methoxymethoxy-5-methyl-phenyl)-N,N-dimethyl-propionamide 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 92-48-8 6-methylcoumarin 
• 1435268-11-3 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-7-yl)(2-(methoxymethoxy)-5-methylphenyl)methanol 
• 1435268-30-6 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-8-yl)(2-(methoxymethoxy)-5-methylphenyl)methanol 
• 1435268-46-4 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-7-yl)(2-(methoxymethoxy)-5-methylphenyl)methanone 
• 1435268-61-3 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-8-yl)(2-(methoxymethoxy)-5-methylphenyl)methanone 
• 1435268-77-1 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-7-yl)(2-hydroxy-5-methylphenyl)methanone 
• 1435268-96-4 (5,6-dimethoxy-2,2-dimethyl-2H-benzopyran-8-yl)(2-hydroxy-5-methylphenyl)methanone 
• 16299-22-2 6-methyl-4-phenylchromen-2-one 
• 40546-94-9 6-methyl-4-phenyl-3,4-dihydrocoumarin 
• 124936-74-9 N,N-diiso-propyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamine 

Relevant articles and documents

Metal-free annulative hydrosulfonation of propiolate esters: synthesis of 4-sulfonates of coumarins and butenolides

An efficient metal-free and cost-effective method for the synthesis of coumarin and butenolide 4-sulfonates (46 examples) has been developed. The reaction involves addition of sulfonic acids to ethyl propiolates followed by lactonization, resulting in direct formation of coumarin and butenolide 4-sulfonates. This methodology has been elaborated to Sonogashira and Suzuki coupling including the synthesis of rac-tolterodine.

Multidimensional optimization of promising antitumor xanthone derivatives

A promising antitumor xanthone derivative was optimized following a multidimensional approach that involved the synthesis of 17 analogues, the study of their lipophilicity and solubility, and the evaluation of their growth inhibitory activity on four human tumor cell lines. A new synthetic route for the hit xanthone derivative was also developed and applied for the synthesis of its analogues. Among the used cell lines, the HL-60 showed to be in general more sensitive to the compounds tested, with the most potent compound having a GI50 of 5.1 μM, lower than the hit compound. Lipophilicity was evaluated by the partition coefficient (Kp) of a solute between buffer and two membrane models, namely liposomes and micelles. The compounds showed a log Kp between 3 and 5 and the two membrane models showed a good correlation (r2 = 0.916) between each other. Studies concerning relationship between solubility and structure were developed for the hit compound and 5 of its analogues.

HETEROAROMATIC-CONTAINING COMPOUND, OPTICAL MATERIAL AND OPTICAL ELEMENT

There are provided a heteroaromatic-containing compound represented by the following general formula (1), and an optical material including the heteroaromatic-containing compound. Formula 1 General Formula (1) wherein R1 and R2 are each independently a hydrogen atom or a methyl group, Ar1 is an aryl group which may have a substituent, and A is an aromatic hydrocarbon group. The R1 and R2 can be a hydrogen atom, and Ar1 can be a phenyl group.