55431-77-1

Basic information

• Product Name: 1,4,4a,9a-tetrahydro-1,4-ethanoanthracene-9,10-dione
• CAS NO: 55431-77-1
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.2812
• Mol File: 55431-77-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 414.2°C at 760 mmHg
• Flash Point: 155°C
• Density: 1.247g/cm³
• Vapor Pressure: 4.54E-07mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 1,4,4a,9a-tetrahydro-1,4-ethanoanthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,4a,9a-tetrahydro-1,4-ethanoanthracene-9,10-dione(55431-77-1)
• EPA Substance Registry System: 1,4,4a,9a-tetrahydro-1,4-ethanoanthracene-9,10-dione(55431-77-1)

Safety Data

• Hazardous Substances Data: 55431-77-1(Hazardous Substances Data)

Usage

Class

Anthracenediones

Function

Cytotoxic chemotherapy drug

Usage

Treatment of various types of cancer, including lung cancer, testicular cancer, and lymphomas

Mechanism of Action

Inhibits the enzyme topoisomerase II, disrupting DNA replication and repair

Effect on Cell Cycle

Triggers the death of cancer cells by blocking topoisomerase II

Side Effects

Bone marrow suppression, increased risk of developing secondary cancers

Importance

Widely used treatment option for cancer patients despite potential risks

Upstream product

• 1165952-91-9 cyclohexa-1,3-diene 
• 106-51-4 p-benzoquinone 
• 130-15-4 [1,4]naphthoquinone 

Downstream Products

• 55431-78-2 1,4,4a,9,9a,10-Hexahydro-1,4-ethano-anthracene-9,10-diol 
• 32740-61-7 1,4-Ethano-1,4-dihydro-9,10-anthraquinone 
• 75102-20-4 1,4-dihydro-9,10-dimethoxy-1,4-ethanoanthracene 
• 75102-24-8 endo-1,4,4a,9a-tetrahydro-4a,9a-epoxy-1,4-ethano-9,10-anthraquinone 
• 75171-67-4 exo-1,4,4a,9a-tetrahydro-4a,9a-epoxy-1,4-ethano-9,10-anthraquinone 
• 84-65-1 9,10-phenanthrenequinone 

Relevant articles and documents

Hydrothermal synthesis of imidazole functionalized carbon spheres and their application in catalysis

We describe the production and catalytic application of highly functionalized mesoporous carbonaceous materials, obtained via a one step green and cheap process relying on the hydrothermal carbonization of carbohydrates (e.g. glucose) in the presence of functional organic monomers (e.g. vinyl imidazole). The resulting materials could be further functionalized to feature imidazolium bromides on their surface and be used for various transesterification, Knoevenagel and Aldol reactions.