75102-24-8

Basic information

• Product Name: 1,4-dihydro-4a,9a-epoxy-1,4-ethanoanthracene-9,10-dione
• CAS NO: 75102-24-8
• Molecular Formula: C₁₆H₁₂O₃
• Molecular Weight: 252.2647
• Mol File: 75102-24-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 472.1°C at 760 mmHg
• Flash Point: 214.3°C
• Density: 1.44g/cm³
• Vapor Pressure: 4.42E-09mmHg at 25°C
• Refractive Index: 1.692
• CAS DataBase Reference: 1,4-dihydro-4a,9a-epoxy-1,4-ethanoanthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dihydro-4a,9a-epoxy-1,4-ethanoanthracene-9,10-dione(75102-24-8)
• EPA Substance Registry System: 1,4-dihydro-4a,9a-epoxy-1,4-ethanoanthracene-9,10-dione(75102-24-8)

Safety Data

• Hazardous Substances Data: 75102-24-8(Hazardous Substances Data)

Usage

Structure

Anthracene core with an epoxy group and a quinone moiety

Applications

Dyes and pigments production
Pharmaceuticals
Antibacterial, antifungal, and antiviral properties

Medical Uses

Chemotherapeutic agents for leukemia, lymphomas, and solid tumors

Additional Properties

Antioxidant effects
Anti-inflammatory effects

Health and Medical Interest

Potential for various health and medical applications due to its antioxidant and anti-inflammatory properties.

Upstream product

• 32740-61-7 1,4-Ethano-1,4-dihydro-9,10-anthraquinone 
• 75172-25-7 C₁₈H₁₈O₄ 
• 132016-30-9 endo-tetracyclo[10.2.2.0^2,11.0^4.9]hexadeca-4,6,8,13-tetraene-3,10-dione 
• 130-15-4 [1,4]naphthoquinone 
• 55431-77-1 (1R,4S)-1,4,4a,9a-Tetrahydro-1,4-ethano-anthraquinone 

Relevant articles and documents

Studies on quinones. Part 40: Synthesis and cytotoxicity evaluation of anthraquinone epoxides and isomerization products

Aerobic oxidation of 1,4,4a,10a-tetrahydro-1,4-alkano-5,10-anthraquinones and thiophene-analogues in dichloromethane-DBU yielded the corresponding dihydroalkanoquinones which, depending on their structures, react with in situ generated hydroperoxide anion to give quinone epoxides and/or hydroperoxides. The calcium hydroxide-induced rearrangement of quinone epoxides yielded furan-containing angular quinones. The cytotoxic activities of quinone epoxides and their isomerization products were evaluated in vitro against normal human lung fibroblasts (MRC-5) and human cancer gastric epithelial cells (AGS).