55476-93-2Relevant articles and documents
Synthesis of Some New Biologically Active 5-Phenoxy-4-phenyl-1,3-thiazol-2-amines.
Ramana, M. M. V.,Dubhashi, Deepnandan S.,D'Souza, Joseph J.
, p. 2563 - 2580 (2007/10/03)
Several new 5-phenoxy-4-phenyl-1,3-thiazol-2-amines have been synthesised via Hantzsch's synthesis and some of these thiazoles have been screened for their in vitro antibacterial activity.
α-Haloalkyl Ethers in Alkylations of 2-Pyrimidinones
Benneche, Tore,Undheim, Kjell
, p. 345 - 350 (2007/10/02)
The ambident 5-halopyrimidin-2-one anion with potassium as counterion in DMF is preferentially O-alkylated using the relatively hard α-chloroalkyl ether electrophiles.As ammonium salts in dichloromethane or by the use of KF-alumina in DME the preference is for N-alkylation.TMS ethers of the pyrimidinones are exclusively N-alkylated.