18859-48-8Relevant articles and documents
Synthesis, X-ray crystal structure and theoretical calculations of antileishmanial neolignan analogues
Do Nascimento, Josenaide P.,Santos, Lourivaldo S.,Santos, Regina Helena A.,Tozzo, E?rica,Ferreira, Janaina G.,Do Carmo, Maria Carolina L.,Brasil, Davi S. B.,Alves, Cla?udio N.
, p. 1825 - 1837 (2010)
The synthesis and X-ray crystal diffraction structure of two analogues of neolignans, 2-(4-chlorophenyl)-1-phenylethanone (20) and 2-[(4-chlorophenyl) thio]-1-(3,4-dimethoxyphenyl)propan-1-one (12) is described. The compound 12 presents activity against i
Palladium-catalyzed α-arylation of aryloxyketones for the synthesis of 2,3-Disubstituted benzofurans
Lee, Jin Ho,Kim, Myungock,Kim, Ikyon
, p. 6153 - 6163 (2014/07/21)
A highly efficient palladium-catalyzed α-arylation of aryloxyketones has been developed, allowing for facile installation of various (hetero)aryl groups at C2 position in good to excellent yields. Subsequent cyclodehydration of the resulting α-arylated ar
ALLOSTERIC PROTEIN KINASE MODULATORS
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Page/Page column 143, (2010/04/30)
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.