55775-97-8 Usage
Description
2,6-Dichloro-3-nitrobenzoic acid (DCNBA) is an organic compound characterized by its molecular structure featuring a benzoic acid backbone with two chlorine atoms at the 2nd and 6th positions, and a nitro group at the 3rd position. It is known for its potential applications in the synthesis of various compounds, particularly those with biological activities.
Uses
Used in Pharmaceutical Industry:
2,6-Dichloro-3-nitrobenzoic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for potential therapeutic applications. Its unique structure allows for the creation of new molecules with potential benefits in the treatment of diseases.
Used in the Synthesis of DNA-Binding Antitumor Agents:
2,6-Dichloro-3-nitrobenzoic acid is used as a starting material for the preparation of 9-chloro-2-methoxy-6-nitro-5,10-dihydrobenzo[b][1,5]naphthyridin-10-one, which is a compound required for the synthesis of potential DNA-binding antitumor agents. These agents may have significant implications in the development of novel cancer treatments.
Used in the Synthesis of Pyrazoloacridines:
DCNBA is also utilized in the preparation of 2-(aminoalkyl)-5-nitropyrazolo[3,4,5-kl]acridines, a class of compounds with potential applications in the pharmaceutical industry, particularly in the development of new drugs with various therapeutic properties.
Used in Analytical Chemistry:
The FT-IR and Raman spectra of 2,6-dichloro-3-nitrobenzoic acid have been investigated, which indicates its potential use in analytical chemistry for the identification and characterization of related compounds through spectral analysis. This can be valuable in both research and quality control processes within the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 55775-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,7 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 55775-97:
(7*5)+(6*5)+(5*7)+(4*7)+(3*5)+(2*9)+(1*7)=168
168 % 10 = 8
So 55775-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H3Cl2NO4/c8-3-1-2-4(10(13)14)6(9)5(3)7(11)12/h1-2H,(H,11,12)
55775-97-8Relevant articles and documents
Structure-activity relationship of novel acridone derivatives as antiproliferative agents
Chen, Ji-Ning,Wu, Xing-Kang,Lu, Chun-Hua,Li, Xun
, (2020/11/18)
Unlike other DNA topoisomerase II (topo II) inhibitors, our recently identified acridone derivative E17 exerted strong cytotoxic activity by inhibiting topo II without causing topo II degradation and DNA damage, which promoted us to explore more analogues
Synthesis method of anti-cancer drug intermediate methyl 2-fluoro-3-aminobenzoate
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Paragraph 0033-0036, (2020/07/13)
The invention discloses a synthetic method of 2-fluoro-3-methyl aminobenzoate, and belongs to the technical field of synthesis of medical intermediates. According to the method, 2, 6-dichlorobenzoic acid is taken as a raw material, 2, 6-dichloro-3-nitrobe
HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS
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Page/Page column 79, (2012/12/13)
The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.
