5580-64-3 Usage
General Description
(2Z)-2-hydroxyimino-N-naphthalen-2-yl-acetamide is a chemical compound with the molecular formula C13H11NO2. It is an organic compound that is often used in laboratory research and chemical synthesis. (2Z)-2-hydroxyimino-N-naphthalen-2-yl-acetamide is characterized by a naphthalene ring structure and a hydroxylamine functional group, and it is commonly used as a reagent in organic chemistry reactions. Additionally, it may have potential applications in the pharmaceutical industry due to its unique chemical properties. The compound may also be used in the development of new materials, such as polymers or coatings, due to its interesting structural features. However, it is important to handle this compound with care, as it may pose health and environmental risks if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 5580-64-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,8 and 0 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5580-64:
(6*5)+(5*5)+(4*8)+(3*0)+(2*6)+(1*4)=103
103 % 10 = 3
So 5580-64-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H10N2O2/c15-12(8-13-16)14-11-6-5-9-3-1-2-4-10(9)7-11/h1-8,16H,(H,14,15)/b13-8+
5580-64-3Relevant articles and documents
Potential Antitumor Agents. 61. Structure-Activity Relationships for in Vivo Colon 38 Activity among Disubstituted 9-Oxo-9H-xanthene-4-acetic Acids
Rewcastle, Gordon W.,Atwell, Graham J.,Zhuang, Li,Baguley, Bruce C.,Denny, William A.
, p. 217 - 222 (2007/10/02)
Analogues of 9-oxo-9H-xanthene-4-acetic acid (XAA) bearing small, lipophilic 5-substituents are among the most dose-potent compounds yet reported with the capability of causing hemorrhagic necrosis of implanted colon 38 tumors in mice.To further extend structure-activity relationships among this class of compound, a series of XAA derivatives bearing two small lipophilic groups at various positions have been prepared and evaluated.The 5,6-disubstituted compounds in particular show consistently high levels of both dose potency and activity, suggesting this is the optimal configuration among substituted 9-oxo-9H-xanthene-4-acetic acids.The 5,6-dimethyl and 5-methyl-6-methoxy are the most effective analogues, showing in vivo colon 38 activity comparable to that of FAA at 10-15-fold lower doses and superior activity to FAA at the respective optimal doses, and the former has been selected for detailed evaluation.
