5586-89-0

Basic information

• Product Name: CINNAMYLAMINE HYDROCHLORIDE
• Synonyms: 3-Phenyl-2-propen-1-amine hydrochloride;CINNAMYLAMINE HYDROCHLORIDE;3-phenyl-2-propen-1-aminhydrochloride;gamma-phenylallylaminehydrochloride;[(2E)-3-Phenylprop-2-en-1-yl]amine hydrochloride;Tranylcypromine Related Compound B (40 mg) (trans-3-phenylallylamine hydrochloride;TranylcyproMine Related CoMpound B;(E)-3-phenylprop-2-en-1-amine hydrochloride
• CAS NO: 5586-89-0
• Molecular Formula: C₉H₁₁N*ClH
• Molecular Weight: 169.65
• Mol File: 5586-89-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 235 °C
• Boiling Point: 253.6°Cat760mmHg
• Flash Point: 105.4°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.0181mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: DMSO (Sparingly, Sonicated), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: CINNAMYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CINNAMYLAMINE HYDROCHLORIDE(5586-89-0)
• EPA Substance Registry System: CINNAMYLAMINE HYDROCHLORIDE(5586-89-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5586-89-0(Hazardous Substances Data)

Usage

Description

Cinnamylamine Hydrochloride is an organic compound derived from the cinnamaldehyde molecule, which is a key component of cinnamon. It is a white crystalline solid with a characteristic aromatic smell. Cinnamyamine Hydrochloride is known for its various applications in the pharmaceutical and chemical industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
Cinnamylamine Hydrochloride is used as a key intermediate compound for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). Tranylcypromine is utilized as an antidepressant and anxiolytic agent, helping to alleviate symptoms of depression and anxiety by regulating the levels of certain neurotransmitters in the brain.

InChI:InChI=1/C9H11N.ClH/c10-8-4-7-9-5-2-1-3-6-9;/h1-7H,8,10H2;1H/b7-4+;

Upstream product

• 146039-13-6 (E)-3-Phenyl-allyl-phosphorimidic acid triethyl ester 
• 85231-94-3 C₁₈H₂₈NO₅P 
• 57294-86-7 (3-azidoprop-1-en-1-yl)benzene 
• 4392-24-9 Cinnamyl bromide 
• 56866-32-1 2-[(E/Z)-3-phenylprop-2-enyl]-2,3-dihydro-1H-isoindole-1,3-dione 
• 4360-51-4 cinnamylamine 

Downstream Products

• 2687-12-9 cinnamyl chloride 
• 1344152-08-4 C₂₃H₂₉NO₉ 

Relevant articles and documents

Catalytic Staudinger Reduction at Room Temperature

We report an efficient catalytic Staudinger reduction at room temperature that enables the preparation of a structurally diverse set of amines from azides in excellent yields. The reaction is based on the use of catalytic amounts of triphenylphosphine as a phosphine source and diphenyldisiloxane as a reducing agent. Our catalytic Staudinger reduction exhibits a high chemoselectivity, as exemplified by reduction of azides over other common functionalities, including nitriles, alkenes, alkynes, esters, and ketones.

Amide and amine nucleophiles in polar radical crossover cycloadditions: Synthesis of γ-lactams and pyrrolidines

In this work we present a direct catalytic synthesis of γ-lactams and pyrrolidines from alkenes and activated unsaturated amides or protected unsaturated amines, respectively. Using a mesityl acridinium single electron photooxidant and a thiophenol cocata

N-(diethoxyphosphoryl)aldimines as synthetic equivalents of A1 type synthons

Novel organophosphorus reagents useful for convergent synthesis of primary amines are presented.