5605-66-3Relevant articles and documents
Synthesis, separation, and characterization of amphiphilic sulfated oligosaccharides enabled by reversed-phase ion pairing LC and LC-MS methods
Fenner, Amanda M.,Kerns, Robert J.
, p. 2792 - 2800 (2011)
Synthesis of amphiphilic oligosaccharides is problematic because traditional methods for separating and purifying oligosaccharides, including sulfated oligosaccharides, are generally not applicable to working with amphiphilic sugars. We report here RPIP-L
Selective inhibition of bacterial and human topoisomerases by N-arylacyl O-sulfonated aminoglycoside derivatives
Fenner, Amanda M.,Oppegard, Lisa M.,Hiasa, Hiroshi,Kerns, Robert J.
supporting information, p. 470 - 474 (2013/07/11)
Numerous therapeutic applications have been proposed for molecules that bind heparin-binding proteins. Development of such compounds has primarily focused on optimizing the degree and orientation of anionic groups on a scaffold, but utility of these polya
A HIGHLY SELECTIVE N-PROTECTION STRATEGY FOR THE PREPARATION OF 1-N-ALKYLATED KANAMYCIN ANTIBIOTICS
Thomas, Michael B.,Williams, Michael T.
, p. 4981 - 4984 (2007/10/02)
An O to N acyl migration technique has been used to selectively acetylate the amino groups of the aminosugar rings of kanamycins A and B, leaving the amino groups on the 2-deoxy-streptamine ring unprotected.A formylation-deformylation process then convert