5623-25-6

Basic information

• Product Name: 1,2-DI-1,1''-BIPHENYL-4-YL-2-HYDROXYETHANONE
• Synonyms: 2-hydroxy-1,2-bis(4-phenylphenyl)ethanone
• CAS NO: 5623-25-6
• Molecular Formula: C₂₆H₂₀O₂
• Molecular Weight: 364.44
• Mol File: 5623-25-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 569.2°Cat760mmHg
• Flash Point: 238.8°C
• Appearance: /
• Density: 1.173g/cm³
• Vapor Pressure: 8.55E-14mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 1,2-DI-1,1''-BIPHENYL-4-YL-2-HYDROXYETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DI-1,1''-BIPHENYL-4-YL-2-HYDROXYETHANONE(5623-25-6)
• EPA Substance Registry System: 1,2-DI-1,1''-BIPHENYL-4-YL-2-HYDROXYETHANONE(5623-25-6)

Safety Data

• Hazardous Substances Data: 5623-25-6(Hazardous Substances Data)

Usage

Derivative of

Biphenyl

Contains

2-hydroxyethyl ketone group

Common use

Building block in the synthesis of various pharmaceuticals and organic compounds

Potential biological activities

Antioxidant and anti-inflammatory properties

Potential applications

Material science and organic chemistry

Structural characteristics

Unique

Research status

Further research needed to fully understand its potential uses and properties

InChI:InChI=1/C26H20O2/c27-25(23-15-11-21(12-16-23)19-7-3-1-4-8-19)26(28)24-17-13-22(14-18-24)20-9-5-2-6-10-20/h1-18,25,27H/t25-/m1/s1

Upstream product

• 4746-80-9 4,4'-diphenylbenzil 
• 3218-36-8 4-Phenylbenzaldehyde 

Downstream Products

• 4746-80-9 4,4'-diphenylbenzil 
• 1657-71-2 cis-4,4'-diphenylstilbene 
• 1694-24-2 1,2-dibiphenylyl-2-ethanone 
• 105770-34-1 Tetrakis-biphenyl-4-yl-furan 
• 1657-73-4 trans-4,4'-diphenylstilbene 
• 13224-48-1 meso-1,2-bis-biphenyl-4-yl-1,2-diphenyl-ethane-1,2-diol 
• 96589-94-5 2,3-di([1,1′-biphenyl]-4-yl)quinoxaline 
• 6334-91-4 4,4'-diphenyl-benzilic acid 

Relevant articles and documents

Organocatalytic Synthesis of Substituted Vinylene Carbonates

The organocatalytic synthesis of substituted vinylene carbonates from benzoins and acyloins was studied using diphenyl carbonate as a carbonyl source. A range of N-Heterocyclic Carbene (NHC) precursors were screened and it was found that imidazolium salts were the most active for this transformation. The reaction occurs at 90 °C under solvent-free conditions. A wide range of substituted vinylene carbonates (symmetrical and unsymmetrical, aromatic or aliphatic), including some derived from natural products, were prepared with 20–99% isolated yields (24 examples). The reaction was also developed using thermomorphic polyethylene-supported organocatalysts as recoverable and recyclable species. The use of such species facilitates the workup and allows the synthesis of vinylene carbonates on the preparative scale (>30 g after 5 runs). (Figure presented.).