56427-98-6

Basic information

• Product Name: Benzene, 1,1'-[oxybis(methylene)]bis[2-chloro-
• CAS NO: 56427-98-6
• Molecular Formula: C14H12Cl2O
• Molecular Weight: 267.155
• Mol File: 56427-98-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[oxybis(methylene)]bis[2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[oxybis(methylene)]bis[2-chloro-(56427-98-6)
• EPA Substance Registry System: Benzene, 1,1'-[oxybis(methylene)]bis[2-chloro-(56427-98-6)

Safety Data

• Hazardous Substances Data: 56427-98-6(Hazardous Substances Data)

Upstream product

• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 
• 150480-30-1 2-chlorobenzyl trimethylsilyl ether 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 17849-38-6 2-Chlorobenzyl alcohol 
• 89-98-5 2-chloro-benzaldehyde 
• 118-91-2 ortho-chlorobenzoic acid 
• 735278-03-2 bis(2-chlorobenzyl) sulfide 
• 1510826-97-7 (5-chloro-2-(1-(methoxyimino)ethyl)phenyl)(2-chlorophenyl)methanone 

Relevant articles and documents

Method for synthesizing ether by catalyzing alcohol through trimethyl halosilane

The invention discloses a method for synthesizing ether by catalyzing alcohol through trimethyl halosilane. According to the method, under the conditions of air or nitrogen atmosphere, no solvent andno transition metal catalyst, an alcohol compound is directly used as a raw material, trimethyl halosilane is used as a catalyst, and symmetric or asymmetric ether is synthesized through one-step selective dehydration reaction. According to the method, the use of strong acid, strong base and organic primary halides with high toxicity, instability and higher price is avoided, the synthesis steps are shortened, the synthesis efficiency is improved, the reaction has good selectivity, and a target ether product can be obtained preferentially.

Aryl Boronic Acid Catalysed Dehydrative Substitution of Benzylic Alcohols for C?O Bond Formation

A combination of pentafluorophenylboronic acid and oxalic acid catalyses the dehydrative substitution of benzylic alcohols with a second alcohol to form new C?O bonds. This method has been applied to the intermolecular substitution of benzylic alcohols to form symmetrical ethers, intramolecular cyclisations of diols to form aryl-substituted tetrahydrofuran and tetrahydropyran derivatives, and intermolecular crossed-etherification reactions between two different alcohols. Mechanistic control experiments have identified a potential catalytic intermediate formed between the aryl boronic acid and oxalic acid.

Synthesis of ethers from carbonyl compounds by reductive etherification catalyzed by iron(III) and silyl chloride

A simple iron- and silyl chloride catalyzed method for the preparation of symmetrical and nonsymmetrical ethers is presented. Various aldehydes and ketones were reductively etherified by using triethylsilane as a reducing agent in the presence of 2 mol% of iron(III) oxo acetate and 8 mol% of chloro(trimethyl)silane. The reactions can be carried out at ambient temperatures and pressures with ethyl acetate as the solvent.