565-23-1

Basic information

• Product Name: Benzene, 1-chloro-4-[(4-fluorophenyl)sulfonyl]-
• CAS NO: 565-23-1
• Molecular Formula: C12H8ClFO2S
• Molecular Weight: 270.712
• Mol File: 565-23-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-[(4-fluorophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-[(4-fluorophenyl)sulfonyl]-(565-23-1)
• EPA Substance Registry System: Benzene, 1-chloro-4-[(4-fluorophenyl)sulfonyl]-(565-23-1)

Safety Data

• Hazardous Substances Data: 565-23-1(Hazardous Substances Data)

Upstream product

• 39055-84-0 1-chloro-4-((4-nitrophenyl)sulfonyl)benzene 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 108-90-7 chlorobenzene 
• 459-45-0 4-fluorobenzenediazonium tetrafluoroborate 
• 106-54-7 p-Chlorothiophenol 
• 462-06-6 fluorobenzene 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 100-03-8 4-chlorobenzenesulfinic acid 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 312-29-8 (4-chloro-3-nitro-phenyl)-(4-fluoro-3-nitro-phenyl)-sulfone 

Relevant articles and documents

Visible-Light-Driven Silver-Catalyzed One-Pot Approach: A Selective Synthesis of Diaryl Sulfoxides and Diaryl Sulfones

An efficient one-pot approach for the synthesis of diaryl sulfoxides and diaryl sulfones using aryl thiols and aryl diazonium salts was developed. The use of a visible-light-driven silver catalysis and the subsequent singlet-oxygen-induced oxidation enabled selective synthesis of sulfoxides and sulfones in the absence of a photocatalyst. The reactions were carried out under mild reaction conditions; the desired products were obtained under air atmosphere at room temperature.

Copper-mediated cascade synthesis of diaryl sulfones via the sandmeyer reaction

A convenient and efficient method for the copper-mediated cascade synthesis of diaryl sulfones via the Sandmeyer reaction has been developed. The protocol uses readily available aryl amines and arylsulfinic acids as the starting materials, isoamyl nitrite as the diazotizating reagent of the aryl amines, and the method shows mild reaction conditions and high tolerance towards various functional groups in the substrates. Georg Thieme Verlag Stuttgart New York.

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.