565203-80-7

Basic information

• Product Name: Benzonitrile, 3-(1,3-benzodioxol-5-yl)-4-methoxy-
• CAS NO: 565203-80-7
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.257
• Mol File: 565203-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 3-(1,3-benzodioxol-5-yl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-(1,3-benzodioxol-5-yl)-4-methoxy-(565203-80-7)
• EPA Substance Registry System: Benzonitrile, 3-(1,3-benzodioxol-5-yl)-4-methoxy-(565203-80-7)

Safety Data

• Hazardous Substances Data: 565203-80-7(Hazardous Substances Data)

Upstream product

• 82504-06-1 3-iodo-4-methoxybenzonitrile 
• 94839-07-3 3,4-(methylenedioxy)-benzeneboronic acid 

Downstream Products

• 565203-90-9 trifluoro-methanesulfonic acid 2-benzo[1,3]dioxol-5-yl-4-cyano-phenyl ester 
• 565203-97-6 3-benzo[1,3]dioxol-5-yl-4-trimethylsilanylethynyl-benzonitrile 
• 565204-04-8 3-benzo[1,3]dioxol-5-yl-4-ethynyl-benzonitrile 
• 450842-25-8 3-(1,3-benzodioxol-5-yl)-4-hydroxybenzonitrile 

Relevant articles and documents

Synthesis and biological evaluation of 4-[3-biphenyl-2-yl-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl]-1- yl-benzonitrile as novel farnesyltransferase inhibitor

Farnesyltransferase inhibitors (FTIs) have emerged as a novel class of anti-cancer agents. Analogues of the potent FTI, 4-[3-biphenyl-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl]-1-yl- benzonitrile, were synthesized and tested in vitro for their inhibitory activities. The synthesis and detailed biological data of this series of analogues are presented.