56961-26-3

Basic information

• Product Name: 2-Bromo-3-chlorobenzoicacid
• Synonyms: Benzoic acid, 2-bromo-3-chloro-
• CAS NO: 56961-26-3
• Molecular Formula: C₇H₄BrClO₂
• Molecular Weight: 235.464
• Mol File: 56961-26-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 330.4 °C at 760 mmHg
• Flash Point: 153.6 °C
• Appearance: /
• Density: 1.809
• Vapor Pressure: 6.67E-05mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.48±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-3-chlorobenzoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-chlorobenzoicacid(56961-26-3)
• EPA Substance Registry System: 2-Bromo-3-chlorobenzoicacid(56961-26-3)

Safety Data

• Hazardous Substances Data: 56961-26-3(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-chlorobenzoic acid is a chemical compound with the molecular formula C7H4BrClO2. It is a derivative of benzoic acid, containing both bromine and chlorine atoms attached to the benzene ring. 2-Bromo-3-chlorobenzoicacid is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also utilized in the production of various organic compounds due to its reactivity and versatility. 2-Bromo-3-chlorobenzoic acid has been studied for its potential biological activities and is of interest in medicinal chemistry for its potential therapeutic applications. Additionally, it is important to handle and store this compound properly, as it is a corrosive substance that can cause skin and eye irritation.

InChI:InChI=1/C7H4BrClO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3H,(H,10,11)

Upstream product

• 69190-56-3 2-bromo-1-chloro-3-methylbenzene 
• 535-80-8 3-chlorobenzoate 
• 694-80-4 2-bromo-1-chlorobenzene 
• 124-38-9 carbon dioxide 
• 104514-49-0 3-chloro-1,2-dibromobenzene 
• 570-24-1 2-Methyl-6-nitroaniline 

Downstream Products

• 116529-64-7 2-bromo-3-chlorobenzoyl chloride 
• 161957-60-4 1-(2-bromo-3-chlorophenyl)ethanone 
• 21739-93-5 2-bromo-5-chlorobenzoic acid 
• 96558-73-5 2-bromo-3-chloro-aniline 
• 1107627-14-4 2-bromo-3-chlorobenzoic acid methyl ester 
• 1448336-70-6 (2-(aminomethyl)-3-chlorophenyl)methanol 
• 1463053-89-5 tert-butyl (2-bromo-3-chlorophenyl)carbamate 
• 27007-53-0 methyl-2-bromo-5-chlorobenzoate 
• 439117-39-2 [2-(aminomethyl)-5-chlorophenyl]methanol 
• 439117-38-1 methyl 5-chloro-2-cyanobenzoate 

Relevant articles and documents

Regioselective halogen-metal exchange reaction of 3-substituted 1,2-dibromo arenes: The synthesis of 2-substituted 5-bromobenzoic acids

Regioselective halogen-metal exchange reactions using isopropylmagnesium chloride were carried out on 3-substituted 1,2-dibromo arenes. Eleven examples are given. Georg Thieme Verlag Stuttgart.

Ortho-metalation of unprotected 3-bromo and 3-chlorobenzoic acids with hindered lithium dialkylamides

Upon treatment of 3-chloro/bromobenzoic acids with hindered lithium dialkylamides (LDA or LTMP) at -50 °C, lithium 3-chloro/bromo-2-lithiobenzoates are generated. These dianions can be trapped as such to afford after electrophilic quenching a variety of s

Lithiations directed by carboxylic acid, fluorine and chlorine: The regioselective synthesis of polysubstituted benzoic acids and acetophenones

Lithiation/electrophilic quenching of ortho-lithiated benzoates allows the totally regiocontrolled synthesis of a wide range of 2,3-, 2,3,4-, and 2,3,4,5-polysubstituted benzoic acids and related acetophenones. Elsevier,.