96558-73-5

Basic information

• Product Name: 2-BROMO-3-CHLOROANILINE
• Synonyms: 2-BROMO-3-CHLOROANILINE;(2-Bromo-3-chlorophenyl)amine;2-broMo-3-chlorobenzenaMine;Benzenamine, 2-bromo-3-chloro
• CAS NO: 96558-73-5
• Molecular Formula: C₆H₅BrClN
• Molecular Weight: 206.4676
• Mol File: 96558-73-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 41-43℃
• Boiling Point: 277℃
• Flash Point: 122℃
• Appearance: /
• Density: 1.722
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 1.48±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-3-CHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-CHLOROANILINE(96558-73-5)
• EPA Substance Registry System: 2-BROMO-3-CHLOROANILINE(96558-73-5)

Safety Data

• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 96558-73-5(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-chloroaniline is a chemical compound with the molecular formula C6H5BrClN. It is a substituted aniline derivative with both bromine and chlorine atoms attached to the benzene ring. It is a white to light brown solid with a faint, sweet odor. 2-Bromo-3-chloroaniline is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also used as a research chemical in organic synthesis and medicinal chemistry. 2-Bromo-3-chloroaniline is considered to be a hazardous chemical and should be handled with caution, as it can cause irritation to the skin, eyes, and respiratory system upon exposure.

InChI:InChI=1/C6H5BrClN/c7-6-4(8)2-1-3-5(6)9/h1-3H,9H2

Upstream product

• 19128-48-4 2-bromo-1-chloro-3-nitro-benzene 
• 56961-26-3 2-bromo-3-chlorobenzoic acid 
• 108-42-9 3-chloro-aniline 
• 863870-78-4 O-2-bromo-3-chlorophenyl N,N-diethylcarbamate 
• 1287791-67-6 2-(2-bromo-3-chlorophenoxy)-2-methylpropanamide 
• 1287791-76-7 N-(2-bromo-3-chlorophenyl)-2-hydroxy-2-methylpropanamide 
• 855836-62-3 2-bromo-3-chlorophenol 
• 159390-33-7 3-chlorophenyl N,N-diethylcarbamate 
• 1463053-89-5 tert-butyl (2-bromo-3-chlorophenyl)carbamate 

Downstream Products

• 908349-50-8 2-bromo-3-chloro-N-trifluoroacetylaniline 
• 908349-52-0 2-bromo-3-chloro-N-methylaniline 
• 908349-53-1 N-allyl-2-bromo-3-chloro-N-methylaniline 
• 908349-54-2 6-allyl-2-bromo-3-chloro-N-methylaniline 
• 908349-51-9 2-bromo-3-chloro-N-methyl-N-trifluoroacetylaniline 

Relevant articles and documents

CINNOLINE DERIVATIVES AS AS BTK INHIBITORS

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined in the specification. The compounds are inhibitors of Bruton's tyrosine

Electrophilic bromination of meta-substituted anilines with N-bromosuccinimide: Regioselectivity and solvent effect

N-Bromosuccinimide-mediated electrophilic aromatic bromination of a series of anilines substituted with an electron-with-drawing group in the meta position was investigated. The regioselectivity of the reaction is markedly dependent on the polarity of the solvent and the bromination reaction can be tuned by appropriate selection of the reaction medium. Georg Thieme Verlag Stuttgart.

Synthesis of anthranylaldoxime derivatives as estrogen receptor ligands and computational prediction of binding modes

N-Me-anthranylaldoximes possess a hydrogen-bonded pseudocyclic A' ring in place of the typical phenolic A-ring that is characteristic of most estrogen receptor (ER) ligands. We have investigated the role played by substituents introduced into either one o