5730-92-7

Basic information

• Product Name: 4-ACETYL-4'-ETHYLBIPHENYL
• Synonyms: 4-ACETYL-4'-ETHYLBIPHENYL
• CAS NO: 5730-92-7
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.3
• Mol File: 5730-92-7.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 350.8 °C at 760 mmHg
• Flash Point: 150.6 °C
• Appearance: /
• Density: 1.023 g/cm³
• CAS DataBase Reference: 4-ACETYL-4'-ETHYLBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETYL-4'-ETHYLBIPHENYL(5730-92-7)
• EPA Substance Registry System: 4-ACETYL-4'-ETHYLBIPHENYL(5730-92-7)

Safety Data

• Hazardous Substances Data: 5730-92-7(Hazardous Substances Data)

Usage

General Description

4-ACETYL-4'-ETHYLBIPHENYL, also known as 4-acetyl-4'-ethylbiphenyl or ethyl-p-acetylbiphenyl, is a chemical compound with the molecular formula C16H14O. It is a derivative of biphenyl with an acetyl group attached to one benzene ring and an ethyl group attached to the other. 4-ACETYL-4'-ETHYLBIPHENYL is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. It is also employed as a key intermediate in the production of dyes, pigments, and other specialty chemicals. 4-ACETYL-4'-ETHYLBIPHENYL is a colorless to pale yellow liquid with a faint odor, and it is considered to be stable under normal conditions of use and storage. However, it may react with strong oxidizing agents and could pose a fire hazard if exposed to heat or flames. Additionally, its potential health hazards include skin and eye irritation, and it may be harmful if swallowed or inhaled. Therefore, appropriate safety measures should be taken when handling and working with this chemical.

Upstream product

• 5707-44-8 4-ethylbiphenyl 
• 75-36-5 acetyl chloride 
• 99-90-1 para-bromoacetophenone 
• 63139-21-9 4-ethylphenylboronic acid 
• 99-91-2 para-chloroacetophenone 
• 92-91-1 biphenyl-4-acetaldehyde 
• 92-52-4 biphenyl 
• 106-43-4 para-chlorotoluene 
• 1585-07-5 1-bromo-4-ethylbenzene 
• 149104-90-5 4-acetylphenylboronic acid 
• 99-93-4 4-Hydroxyacetophenone 
• 133042-62-3 4-acetylphenyl sulfurofluoridate 
• 13049-40-6 4,4'-diethylbiphenyl 

Downstream Products

• 13049-40-6 4,4'-diethylbiphenyl 
• 5731-13-5 4-(4-ethylphenyl)benzoic acid 

Relevant articles and documents

HCl-Catalyzed Aerobic Oxidation of Alkylarenes to Carbonyls

The construction of C?O bonds through C?H bond functionalization remains fundamentally challenging. Here, a practical chlorine radical-mediated aerobic oxidation of alkylarenes to carbonyls was developed. This protocol employed commercially available HCl as a hydrogen atom transfer (HAT) reagent and air as a sustainable oxidant. In addition, this process exhibited excellent functional group tolerance and a broad substrate scope without the requirement for external metal and oxidants. The mechanistic hypothesis was supported by radical trapping, 18O labeling, and control experiments.

Selective electrochemical oxidation of aromatic hydrocarbons and preparation of mono/multi-carbonyl compounds

A selective electrochemical oxidation was developed under mild condition. Various mono-carbonyl and multi-carbonyl compounds can be prepared from different aromatic hydrocarbons with moderate to excellent yield and selectivity by virtue of this electrochemical oxidation. The produced carbonyl compounds can be further transformed into α-ketoamides, homoallylic alcohols and oximes in a one-pot reaction. In particular, a series of α-ketoamides were prepared in a one-pot continuous electrolysis. Mechanistic studies showed that 2,2,2-trifluoroethan-1-ol (TFE) can interact with catalyst species and generate the corresponding hydrogen-bonding complex to enhance the electrochemical oxidation performance. [Figure not available: see fulltext.]

A one-pot protocol for the fluorosulfonation and Suzuki coupling of phenols and bromophenols, streamlined access to biaryls and terphenyls

A one-pot protocol for the fluorosulfation and Suzuki coupling of phenols is described. The tandem reaction proceeds efficiently at room temperature, and various biaryls and biaryl fluorosulfates were obtained in good to excellent yields. Furthermore, biaryl fluorosulfates were utilized as versatile building blocks for the preparation of terphenyls. The Royal Society of Chemistry 2020.