57440-43-4Relevant articles and documents
Electrochemical Oxidation Enables Regioselective and Scalable α-C(sp3)-H Acyloxylation of Sulfides
Wang, Huamin,He, Meng,Li, Yongli,Zhang, Heng,Yang, Dali,Nagasaka, Masanari,Lv, Zongchao,Guan, Zhipeng,Cao, Yangmin,Gong, Fengping,Zhou, Zhilin,Zhu, Jingyun,Samanta, Supravat,Chowdhury, Abhishek Dutta,Lei, Aiwen
supporting information, p. 3628 - 3637 (2021/04/07)
A highly selective, environmentally friendly, and scalable electrochemical protocol for the construction of α-acyloxy sulfides, through the synergistic effect of self-assembly-induced C(sp3)-H/O-H cross-coupling, is reported. It features exceptionally broad substrate scope, high regioselectivity, gram-scale synthesis, construction of complex molecules, and applicability to a variety of nucleophiles. Moreover, the soft X-ray absorption technique and a series of control experiments have been utilized to demonstrate the pivotal role of the self-assembly of the substrates, which indeed is responsible for the excellent compatibility and precise control of high regioselectivity in our electrochemical protocol.
Synthesis of α-Haloalkyl Esters from α-Arylthioalkyl Esters
Benneche, Tore,Strande, Per,Wiggen, Unni
, p. 74 - 77 (2007/10/02)
α-Monohaloalkyl esters have been prepared under mild conditions in high yields by selective cleavage of the carbon-sulfur bond in α-phenylthioalkyl esters using sulfuryl chloride or bromine.The intermediate α-phenylthioalkyl esters have been prepared by alkylation of the corresponding carboxylic acids with readily accessible α-haloalkyl phenyl sulphides.
