57486-71-2

Basic information

• Product Name: 2-(3,4-dimethylphenyl)acetic acid methyl ester
• Synonyms: 2-(3,4-dimethylphenyl)acetic acid methyl ester
• CAS NO: 57486-71-2
• Molecular Weight: 178.231
• Mol File: 57486-71-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dimethylphenyl)acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethylphenyl)acetic acid methyl ester(57486-71-2)
• EPA Substance Registry System: 2-(3,4-dimethylphenyl)acetic acid methyl ester(57486-71-2)

Safety Data

• Hazardous Substances Data: 57486-71-2(Hazardous Substances Data)

Usage

Molecular class

Aromatic acetates

Derivative

2-(3,4-dimethylphenyl)acetic acid methyl ester

Usage

Organic synthesis, intermediate in pharmaceuticals and agrochemicals production

Physical property

Strong aroma

Application

Fragrance industry

Therapeutic potential

Inflammation and pain treatment

Industry applications

Wide range due to chemical properties and potential benefits.

Upstream product

• 3637-01-2 3,4-dimethylacetophenone 
• 102-46-5 4-(chloromethyl)-1,2-dimethylbenzene 
• 67-56-1 methanol 
• 3020-06-2 3,4-dimethylphenylacetonitrile 

Downstream Products

• 503597-07-7 2-(3,4-dimethylphenethyl)-1,3-propanediol 
• 503597-27-1 ethyl 2-amino-4-(3,4-dimethylphenyl)butanoate 
• 503597-09-9 4-(3,4-dimethylphenyl)-2-(hydroxymethyl)butyl pivalate 
• 503597-05-5 diethyl 2-(3,4-dimethylphenethyl)malonate 
• 503598-02-5 2,2-dimethyl-propionic acid 2-aminomethyl-4-(3,4-dimethyl-phenyl)-butyl ester 
• 503597-29-3 tert-butyl N-[3-(3,4-dimethylphenyl)-1-(hydroxymethyl)propyl]carbamate 
• 503597-11-3 2-(azidomethyl)-4-(3,4-dimethylphenyl)butyl pivalate 
• 503597-28-2 ethyl 2-(tert-butoxycarbonylamino)-4-(3,4-dimethylphenyl)butanoate 
• 503597-31-7 2-[(tert-butoxycarbonyl)amino]-4-(3,4-dimethylphenyl)butyl pivalate 
• 503597-26-0 ethyl 4-(3,4-dimethylphenyl)-2-[(diphenylmethylene)amino]butanoate 
• 503597-34-0 N-[4-(3,4-dimethylphenyl)-1-pivaloyloxy-2-butyl]-N'-[3-methoxy-4-(methoxymethoxy)benzyl]thiourea 
• 503597-14-6 N-[4-(3,4-dimethylphenyl)-2-(pivaloyloxymethyl)butyl]-N'-[3-methoxy-4-(methoxymethoxy)benzyl]thiourea 
• 103323-56-4 2-(3',4'-dimethylphenyl)ethyl bromide 
• 1186201-07-9 Methyl 1-(3,4-dimethylphenyl)-1-bromoacetate 

Relevant articles and documents

PROCESS FOR PRODUCTION OF THIOPHENE COMPOUND AND INTERMEDIATE THEREOF

To provide a novel process for producing a 2-aryl-3-hydroxy-4-substituted carbonyl thiophene compound or an intermediate thereof useful as an intermediate for production of medicines and agricultural chemicals. A 2-aryl acetate compound represented by the formula (1): wherein R1 is an aryl group or the like, R4 is a C1-3 alkyl group or the like, and X is a leaving group, is reacted with a thioacetic acid compound to form a thioacetyl compound (3), the thioacetyl compound (3) is reacted with a vinyl ketone compound to form a γ-ketosulfide compound (5), which is cyclized under basic conditions to form a dihydrothiophene compound (6), and the dihydrothiophene compound (6) is oxidized by using an oxidizing agent to produce a 2-aryl-3-hydroxy-4-substituted carbonyl thiophene compound (7).

Muscarinic receptor antagonists

Muscarinic receptor antagonists of formula (I), and their pharmaceutically acceptable salts, wherein Y is --CH 2 --, --(CH 2) 2 --, --CH 2 O--, --(CH 2) 2 O-- or --CH 2 S--; R is --CH or --CONH 2 ; and R 1 is a group of formula (a), where R 2 and R 3 are each independently H, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, --(CH 2) n OH, halo, trifluoromethyl, cyano, --(CH 2) n NR 4 R 5, --CO(C 1 -C 4 alkyl), --OCO(C 1 -C 4 alkyl), --CH(OH)(C 1 -C 4 alkyl), --C(OH)(C 1 -C 4 alkyl 2, --SO 2 NH 2, --(CH 2) n CONR 6 R 7 or --(CH 2) n COO(C 1 -C 4 alkyl); R 4 is H or C 1 -C 4 alkyl; R 5 is H, C 1 -C 4 alkyl or C 1 -C 4 alkysulphonyl; R 6 and R 7 are each independently H or C 1 -C 4 alkyl; and n is 0, 1 or 2. The compounds are particularly useful in treating irritable bowel syndrome.