58110-89-7Relevant articles and documents
PYRANOCHROMENYLPHENOL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC SYNDROME OR INFLAMMATORY DISEASE
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Paragraph 0078, (2016/11/28)
Provided is a compound of the following Formula (I), a pharmaceutically acceptable salt thereof, or a solvate thereof. Further, provided is a pharmaceutical composition for preventing or treating a metabolic syndrome or an inflammatory disease, including the same. in the formula, R1 is a hydrogen atom, methyl, methoxy, or a halogen atom; R2 is a hydrogen atom; a substituted or unsubstituted straight or branched C1-C6 alkyl group; a halogen atom; a substituted or unsubstituted straight or branched C1-C6 alkoxy group; or a substituted or unsubstituted straight or branched C1-C4 thioalkyl group; R3 and R4 are each independently a hydrogen atom, or a C1-C2 alkyl group; and in the case of the substituted alkyl, the substituted alkoxy, and the substituted thioalkyl, the substituent is a straight or branched C1-C5 alkyl group, a halogen atom, a straight or branched C1-C5 alkoxy group, or a straight or branched C1-C3 thioalkyl group.
SAR studies of epoxycurcuphenol derivatives on leukemia CT-CD4 cells
Galindo, José L.G.,Macías, Mariola,Molinillo, José M.G.,Mu?oz-Suano, Alba,Torres, Ascensión,Varela, Rosa M.,García-Cozar, Francisco,Macías, Francisco A.
supporting information, p. 6662 - 6668 (2013/01/15)
Bioactive natural products are a potential source of new pharmaceuticals since they offer new modes of action and more specific activities. The use of derivatization also enables the optimal structure for their biological activity to be determined. In thi
Efficient total synthesis of racemic bisabolane sesquiterpenes curcuphenol and xanthorrhizol starting from substituted acetophenones
Montiel, Luisa E.,Zepeda, L. Gerardo,Tamariz, Joaquin
experimental part, p. 1261 - 1273 (2010/09/07)
A total synthesis of natural bisabolane sesquiterpenes curcuphenol (1) and xanthorrhizol (2) was developed by using the substituted acetophenones 4 and 5, respectively, as starting materials. The acetyl group of the latter was activated through ethoxycarb