58196-33-1

Basic information

• Product Name: 7-Hydroxy-1,2,3,4-tetrahydroquinoline
• Synonyms: 7-Hydroxy-1,2,3,4-Tetrahydro Quinolinoe;7-Hydroxy-1,2,3,4-tetrahydroquinoline;7-hydroxy-1,2,3,4-Tetrahydro-quinolin;1,2,3,4-Tetrahydro-quinolin-7-ol;1,2,3,4-Tetrahydro-7-quinolinol;7-Quinolinol, 1,2,3,4-tetrahydro-
• CAS NO: 58196-33-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• EINECS: -0
• Mol File: 58196-33-1.mol
• Article Data: 30

Chemical Properties

• Melting Point: 70-80 °C
• Boiling Point: 319.7 °C at 760 mmHg
• Flash Point: 174.7 °C
• Appearance: /
• Density: 1.141 g/cm₃
• Vapor Pressure: 0.000611mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• PKA: 10.70±0.20(Predicted)
• Stability: Light Sensitive
• CAS DataBase Reference: 7-Hydroxy-1,2,3,4-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Hydroxy-1,2,3,4-tetrahydroquinoline(58196-33-1)
• EPA Substance Registry System: 7-Hydroxy-1,2,3,4-tetrahydroquinoline(58196-33-1)

Safety Data

• Hazardous Substances Data: 58196-33-1(Hazardous Substances Data)

Usage

General Description

7-Hydroxy-1,2,3,4-tetrahydroquinoline is a chemical compound from the tetrahydroquinoline family. It is a hydroxy derivative of tetrahydroquinoline, which is a heterocyclic compound, featuring a four-membered ring fused with a benzene ring. 7-Hydroxy-1,2,3,4-tetrahydroquinoline, being related to a class of molecules that have been studied for their biological activity, could have potential applications in medicinal chemistry. It's important to handle this compound with care as its risks and safety measures have not been fully explored. Its properties such as solubility, stability, and reactivity are crucial factors for chemists in determining its possible applications.

InChI:InChI=1/C9H11NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1,3,5,10-11H,2,4,6H2

Upstream product

• 580-20-1 quinolin-7-ol 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 1023913-73-6 7-methoxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 
• 19500-61-9 7-methoxy-1,2,3,4-tetrahydroquinoline 
• 4964-76-5 7-methoxyquinoline 
• 879-56-1 7-Methoxy-2,3-dihydro-1H-quinolin-4-one 
• 3334-67-6 3-((3-methoxyphenyl)amino)propanoic acid 
• 536-90-3 m-Anisidine 
• 179897-99-5 1-tert-butoxycarbonyl-1,2,3,4-tetrahydro-7-methyloxy-4-quinolinone 
• 153856-89-4 7-amino-1,2,3,4-tetrahydroquinoline 
• 22246-18-0 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone 

Downstream Products

• 94411-96-8 7-hydroxy-1-methyl-1,2,3,4-tetrahydroquinoline 
• 62669-73-2 coumarin 339 
• 53518-16-4 4-trifluoromethyl-6,7,8,9-tetrahydro-pyrano[3,2-g]quinolin-2-one 
• 944413-76-7 C₁₉H₁₅NO₃ 
• 71130-68-2 1-ethyl-7-hydroxy-1,2,3,4-tetrahydroquinoline 
• 1345614-76-7 3-[7-(tert-butyldimethylsilanyloxy)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-phenylethyl ester 
• 1345614-77-8 acetic acid 4-(1{3-[7-(tert-butyldimethylsilanyloxy)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonyloxy}-2,2,2-trifluoroethyl)phenyl ester 
• 1345614-78-9 1,11-bis[3-(2,2,2-trifluoro-1-phenylethoxysulfonyl)propyl]-3,4,8,9,10,11-hexahydro-2H-13-oxa-6,11-diaza-1-azonia-pentacene chloride 
• 1345614-80-3 1,11-bis{3-[1-(4-acetoxyphenyl)-2,2,2-trifluoroethoxysulfonyl]propyl}-3,4,8,9,10,11-hexahydro-2H-13-oxa-6,11-diaza-1-azonia-pentacene tetrafluoroborate 
• 1345614-75-6 3-(7-methoxy-3,4-dihydro-2H-quinolin-1-yl)propane-1-sulfonic acid 2,2,2-trifluoro-1-phenylethyl ester 
• 1429922-14-4 3-(1-ethyl-1,2,3,4-tetrahydroquinolin-7-yloxy)aniline 

Relevant articles and documents

Development of a C2-Symmetric Chiral aza Spirocyclic Diol

A C2-symmetric chiral spirocyclic diol aza-SPINOL containing a spirooxindole scaffold has been designed, synthesized, and optically resolved. The product could be synthesized on gram scale in an overall yield of 22%. Moreover, elaborations of aza-SPINOL to other chiral ligands as well as the preliminary investigation of the related bisphosphine ligand in the desymmetrization of bisallylic amide were reported.

Cu-Catalyzed Chemoselective Reduction of N-Heteroaromatics with NH3·BH3 in Aqueous Solution

An efficient catalytic system was successfully developed on reduction of N-heteroaromatics with H3N?BH3 as hydrogen source in CuSO4 solution, featuring excellent chemoselectivity as well as very broad functional group tolerance. Various challenging substrates, such as OH-, NH2-, Cl-, Br-, etc., contained quinolines, quinoxalines, 1,5-naphthyridines and quinazolines were all reduced smoothly. Mechanistic studies suggested that [Cu-H] intermediate might be generated from NH3?BH3, which was believed to form with H3N?BH3 in CuSO4 solution.

NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION

Nerve-specific fluorophore formulations for direct or systemic administration are described. The formulations can be used in fluorescence-guided surgery (FGS) to aid in nerve preservation during surgical interventions.