58200-88-7 Usage
General Description
6-amidino-2-naphthol is a chemical compound that belongs to the class of organic compounds known as naphthols, which are naphthalene derivatives characterized by the presence of one or more hydroxyl groups on the naphthalene ring. It is distinguished by the presence of an amidine group. Its systematic name is 2-Naphthol, 6-(aminoiminomethyl)-. However, there is not much scientific literature or detailed information available regarding this compound, its properties or its uses; it is therefore assumed that this chemical is not commonly used or well-studied in scientific research, indicating that 6-amidino-2-naphthol may not have notable practical applications or health implications.
Check Digit Verification of cas no
The CAS Registry Mumber 58200-88-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58200-88:
(7*5)+(6*8)+(5*2)+(4*0)+(3*0)+(2*8)+(1*8)=117
117 % 10 = 7
So 58200-88-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H10N2O/c12-11(13)9-2-1-8-6-10(14)4-3-7(8)5-9/h1-6H,12-13H2
58200-88-7Relevant articles and documents
Inhibition of the tissue factor/factor VIIa complex - Lead optimisation using combinatorial chemistry
Roussel, Patrick,Bradley, Mark,Kane, Peter,Bailey, Christine,Arnold, Ruth,Cross, Andrew
, p. 6219 - 6230 (2007/10/03)
Following a high throughput screen (HTS) for the inhibition of the tissue factor/factor VIIa complex and the identification of a number of original hits a lead optimisation programme was initiated to improve their potency. This necessitated the development of an amidine based linker which allowed the generation of a library of amidinonaphthols prepared both by multiple parallel synthesis (MPS) and split and mix methods. The most active compound had an IC50 of 4μM some 10x more potent than the original lead compound.
Synthetic inhibitors of serine proteinases
Wagner,Lischke,Markwardt,et al.
, p. 761 - 763 (2007/10/05)
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