58432-84-1 Usage
Description
3,4-DiMethoxy-6-iodophenylacetonitrile is an organic chemical compound characterized by the presence of two methoxy groups at the 3rd and 4th positions, an iodine atom at the 6th position, and a nitrile group attached to a phenyl ring. This unique structure makes it a valuable intermediate in the synthesis of various pharmaceutical and chemical compounds.
Uses
Used in Pharmaceutical Industry:
3,4-DiMethoxy-6-iodophenylacetonitrile is used as an intermediate for the preparation of halogenated dopamine analogues, which are essential in tissue distribution studies. These analogues help researchers understand the distribution and behavior of dopamine in different tissues, providing valuable insights into the development of drugs targeting dopamine-related disorders.
Used in Chemical Research:
3,4-DiMethoxy-6-iodophenylacetonitrile is also used as a key intermediate in the synthesis of various chemical compounds, particularly those involving the modification of phenyl rings. Its unique structure allows for the development of new compounds with potential applications in various fields, such as materials science, agrochemicals, and more.
Check Digit Verification of cas no
The CAS Registry Mumber 58432-84-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,4,3 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58432-84:
(7*5)+(6*8)+(5*4)+(4*3)+(3*2)+(2*8)+(1*4)=141
141 % 10 = 1
So 58432-84-1 is a valid CAS Registry Number.
58432-84-1Relevant articles and documents
A ring-closing metathesis-based approach to the synthesis of (+)-tetrabenazine
Johannes, Manuel,Altmann, Karl-Heinz
supporting information; experimental part, p. 3752 - 3755 (2012/09/07)
A modular stereoselective synthesis of the vesicular monoamine transport inhibitors (+)-tetrabenazine ((+)-1) and (+)-α-dihydrotetrabenazine ((+)-2) has been developed. The approach is based on amine 4 and acid 5 as the key building blocks, which were elaborated into macrolactam 3 by amide coupling and a subsequent highly E-selective RCM reaction. Macrolactam 3 could be converted into tetrabenazine in three known steps.
An improved stereocontrolled route to cis-erythrinanes by combined intramolecular Strecker and Bruylants reaction
Reimann, Eberhard,Ettmayr, Christian
, p. 1143 - 1155 (2007/10/03)
Condensation of (2-iodophenyl)ethylamines with cyclohexanoylacetaldehyde provided the corresponding aldimines which were reduced yielding secondary phenethylcyclohexanoylethylamines. These in turn were appropriate intermediates to prepare several erythrin
