58512-50-8

Basic information

• Product Name: 1,4-Cyclohexanediol, monoacetate
• Synonyms: 1,4-Cyclohexandiol-monoacetat;1,4-Cyclohexanediol,monoacetate;4-hydroxycyclohexyl acetate;1,4-Cyclohexanediol,monoacetate,trans;4-acetoxycyclohexanol;4-acetoxycyclohexan-1-ol
• CAS NO: 58512-50-8
• Molecular Formula: C8H14O3
• Molecular Weight: 158.197
• Mol File: 58512-50-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 68-72 °C
• Boiling Point: 136-137 °C(Press: 15 Torr)
• Density: 1.09±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1,4-Cyclohexanediol, monoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Cyclohexanediol, monoacetate(58512-50-8)
• EPA Substance Registry System: 1,4-Cyclohexanediol, monoacetate(58512-50-8)

Safety Data

• Hazardous Substances Data: 58512-50-8(Hazardous Substances Data)

Usage

Physical state

Clear, colorless liquid

Uses

a. Solvent in industrial processes
b. Intermediate in chemical synthesis
c. Additive in various applications

Primary applications

a. Production of polymers
b. Production of resins
c. Production of coatings

Potential applications

a. Synthesis of pharmaceuticals
b. Synthesis of fine chemicals

Toxicity

Low toxicity

Environmental impact

Not considered a significant environmental hazard

Safety precautions

Proper handling and storage procedures should be followed to prevent potential risks associated with its use.

Upstream product

• 556-48-9 1,4-Cyclohexanediol 
• 108-24-7 acetic anhydride 
• 830-03-5 4-nitrophenol acetate 
• 1036648-30-2 4-acetoxycyclohexyl 4-methylbenzoate 
• 622-45-7 cyclohexyl acetate 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 108-22-5 Isopropenyl acetate 
• 637-88-7 1,4-Cyclohexanedione 

Downstream Products

• 622-45-7 cyclohexyl acetate 
• 1262219-79-3 4-[(diphenylphosphoryl)oxy]cyclohexyl acetate 
• 101489-34-3 (4-Acetoxy-1-hydroxy-cyclohexyl)-acetic acid ethyl ester 
• 101489-33-2 (4-Acetoxy-1-hydroxy-cyclohexyl)-acetic acid ethyl ester 
• 105814-59-3 Acetic acid 2-(4-acetoxy-1-hydroxy-cyclohexyl)-ethyl ester 
• 101489-38-7 trans-1-(2-hydroxyethyl)cyclohexane-1,4-diol 
• 93675-85-5 rengyol 
• 10437-78-2 3-cyclohexen-1-yl acetate 
• 41043-88-3 4-acetoxycyclohexanone 

Relevant articles and documents

Hyperconjugation and the increasing bulk of OCOCX3 substituents in trans-1,4-disubstituted cyclohexanes destabilize the diequatorial conformer

The trans diesters of 1,4-cyclohexanediol with a number of acetic acid analogues, CX3COOH, of varying steric hindrance and polarity (CX 3 = Me, Et, iso-Pr, tert-Bu, CF3, CH2Cl, CHCl2, CCl3,

HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS

The invention relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): (I), wherein L1, A, X1, X2, R1, R2, and R3 are described herein.

Novel electrochemical deoxygenation reaction using diphenylphosphinates

The electrochemical reduction of diphenylphosphinate esters leads smoothly and in high yields to the corresponding deoxygenated products. In comparison with the previously developed methodologies, the electrolysis could be performed at lower temperature and with a higher current density, resulting in a shorter reaction time.