5864-38-0

Basic information

• Product Name: 9-Isoestradiol
• CAS NO: 5864-38-0
• Molecular Formula: C₁₈H₂₄O₂
• Molecular Weight: 272.387
• Mol File: 5864-38-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 445.9°Cat760mmHg
• Flash Point: 209.6°C
• Density: 1.17g/cm³
• CAS DataBase Reference: 9-Isoestradiol(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Isoestradiol(5864-38-0)
• EPA Substance Registry System: 9-Isoestradiol(5864-38-0)

Safety Data

• Hazardous Substances Data: 5864-38-0(Hazardous Substances Data)

Upstream product

• 19973-76-3 (+/-)-oestrone 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 75863-24-0 (1Ξ,5SR)-1-Methyl-2-oxo-5-vinylcyclopentan-1,3-dicarbonsaeure-dimethylester 
• 80868-65-1 2-Trimethylsilyl-1-(4-methoxy-2-methylphenyl)prop-2-en-1-ol 
• 75863-10-4 <(6Ξ,7SR)-6-Methyl-1,4-dioxaspiro<4.4>non-7-yl>essigsaeure-methylester 
• 75863-12-6 (6Ξ,7SR)-6-Methyl-7-vinyl-1,4-dioxaspiro<4.4>nonan 
• 75863-11-5 2-<(6Ξ,4SR)-6-Methyl-1,4-dioxaspiro<4.4>non-7-yl>ethanol 
• 80868-64-0 1-(4-Methoxy-2-methylphenyl)prop-2-en-1-ol 
• 80868-66-2 1-(4-Methoxy-2-methylphenyl)prop-2-en-1-on 
• 75863-25-1 2-Trimethylsilyl-1-(4-methoxy-2-methylphenyl)prop-2-en-1-on 
• 57069-78-0 <(1SR,2Ξ)-2-Methyl-3-oxocyclopentyl>essigsaeure-methylester 
• 63518-90-1 (2Ξ,3SR)-2-Methyl-3-vinylcyclopentan-1-on 
• 17447-60-8 dimethyl 2-vinylcyclopropane-1,1-dicarboxylate 
• 27060-75-9 4-bromo-3-methylanisole 

Downstream Products

• 1474-52-8 17β-oestradiol diacetate 
• 88847-87-4 2-chloro-17β-oestradiol 
• 15833-07-5 2-bromo-17β-oestradiol 
• 24381-12-2 2-iodo-17β-oestradiol 
• 1743-60-8 17-β-estradiol 17-acetate 

Relevant articles and documents

An environmentally friendly and cost effective synthesis of estradiol featuring two novel reagents: Si(0)/KF and PMHS/hexamethyldisiloxane/pTSA

Si(0)/KF is introduced as a strong, inexpensive, environmentally friendly, and safe reagent for 'dissolving metal'-type reduction. PMHS/hexamethyldisiloxane/pTSA is introduced as an inexpensive substitute for Et3SiH/TFA for 'ionic hydrogenation', where the hexamethyldisiloxane functions as a capping agent to block the oligomeric silicone by-product from cross-linking to a gel, rubber, or plastic. An environmentally friendly and cost effective synthesis of estradiol is described which showcases these new reagents.

Highly selective total synthesis of 19-nor-steroids via a photochemical key reaction: Racemic target compounds

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Asymmetric total synthesis of estradiol by an intramolecular cycloaddition of benzocyclobutene derivative

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