586415-11-4

Basic information

• Product Name: Benzoic acid, 2-(2,2-dichloroethenyl)-5-methoxy-
• Synonyms: 2-(2,2-Dichlor-vinyl)-5-methoxy-benzoesaeure;2-(2,2'-dichloroethenyl)-5-methoxybenzoic acid;2-(2,2-dichloro-vinyl)-5-methoxy-benzoic acid;Benzoic acid,2-(2,2-dichloroethenyl)-5-methoxy
• CAS NO: 586415-11-4
• Molecular Formula: C10H8Cl2O3
• Molecular Weight: 247.078
• Mol File: 586415-11-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 399.9±42.0 °C(Predicted)
• Density: 1.428±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-(2,2-dichloroethenyl)-5-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2,2-dichloroethenyl)-5-methoxy-(586415-11-4)
• EPA Substance Registry System: Benzoic acid, 2-(2,2-dichloroethenyl)-5-methoxy-(586415-11-4)

Safety Data

• Hazardous Substances Data: 586415-11-4(Hazardous Substances Data)

Upstream product

• 586-38-9 3-Methoxybenzoic acid 
• 586415-12-5 2-(β,β-dichloroethenyl)-5-hydroxybenzoic acid 
• 77-78-1 dimethyl sulfate 
• 82735-28-2 6-methoxy-3-(trichloromethyl)isobenzofuran-1(3H)-one 

Downstream Products

• 1370022-17-5 (3R,4R)-methyl 7-methoxy-1-oxo-3-phenylisochroman-4-carboxylate 
• 1370022-14-2 C₁₇H₁₄O₅ 
• 1225021-05-5 6-(4-hydroxyphenyl)-3,9-dimethoxy-5H-indeno[1,2-c] isoquinoline-5,11(6H)-diketone 
• 1419828-48-0 7-methoxy-3-(4-methoxyphenyl)-2-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)isoquinolin-1(2H)-one 
• 1419828-56-0 7-methoxy-3-(4-methoxyphenyl)-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)isoquinolin-1(2H)-one 

Relevant articles and documents

Rapid access of some chloro-substituted isocoumarins and biological activity toward some pathogenic systems

Sulphuric acid-catalyzed chloralhydrate condensation with different m-substituted benzoic acids formed trichlorophthalides 1, from which Zn + AcOH reduction afforded various dichloro derivatives 2. These derivatives 2 on treatment with alkaline Hg(OAc)su

3-PHENYL-7-HYDROXY-ISOCOUMARINS AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS

This invention relates to 3-phenyl-7-hydroxy-isocoumarin compounds which are MIF inhibitors, compositions comprising said inhibitors and methods for treating or preventing diseases associated with MIF.

ENANTIOSELECTIVE ORGANIC ANHYDRIDE REACTIONS

Disclosed herein is enantioselective synthetic method comprising reacting an enolisable C4-C50 organic anhydride with a second compound selected from the group consisting of an aldehyde, a ketone, an aldimine, a ketimine or a Michael Acceptor in the presence of a bifunctional organocatalyst. The reaction may find particular utility in the enantioselective synthesis of medicinally relevant heterocycles, such as dihydroisocoumarins and dihydroisoquinolinones.