58759-08-3

Basic information

• Product Name: oxo(thiophen-3-yl)acetaldehyde
• CAS NO: 58759-08-3
• Molecular Formula: C₆H₄O₂S
• Molecular Weight: 140.1598
• Mol File: 58759-08-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 210.5°C at 760 mmHg
• Flash Point: 81.1°C
• Density: 1.3g/cm³
• Vapor Pressure: 0.192mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: oxo(thiophen-3-yl)acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: oxo(thiophen-3-yl)acetaldehyde(58759-08-3)
• EPA Substance Registry System: oxo(thiophen-3-yl)acetaldehyde(58759-08-3)

Safety Data

• Hazardous Substances Data: 58759-08-3(Hazardous Substances Data)

Upstream product

• 1468-83-3 1-(thiophen-3-yl)-ethanone 

Downstream Products

• 112600-80-3 [3]thienyl-glyoxal-bis-phenylhydrazone 
• 91793-49-6 S-(+)-(thienyl-3)-2 cyclohexyl-2 hydroxy-2 ethanal 
• 120199-41-9 S-(-)-(thienyl-3)-1 cyclohexyl-1 ethanediol-1,2 
• 91741-41-2 S-(-)-(thienyl-3)-2 cyclohexyl-2 hydroxy-2 acetate de methyle 
• 91704-71-1 (-)-2S,3'R-3-quinuclidinyl 2-(3-thienyl)-2-cyclohexyl-2-hydroxy-acetate 
• 91704-71-1 (-)-2S,3'S-3-quinuclidinyl 2-(3-thienyl)-2-cyclohexyl-2-hydroxy-acetate 
• 1351707-62-4 2,6-dimethyl-4-[6-(3-thienyl)-1,2,5-oxadiazolo[3,4-b]pyrazin-5-yl]phenol 
• 1351707-64-6 2,6-di-tert-butyl-4-[6-(3-thienyl)-1,2,5-oxadiazolo[3,4-b]pyrazin-5-yl]phenol 

Relevant articles and documents

Design and synthesis of 2-acylbenzothiazoles via in situ cross-trapping strategy from benzothiazoles with aryl ketones

An I2/KOH synergistically promoted direct ring-opening aroylation of benzothiazoles with aryl ketones has been discovered. Aryl ketones were seen to act as carbonyl sources to construct 2-acylbenzothiazoles. This reaction could provide an example for the convergent integration of self-labor domino sequences based on an in situ cross-trapping strategy.

Dedoublement et determination de la configuration absolue des enantiomeres de l'acide (thienyl-3)-2 cyclohexyl-2 hydroxy-2 acetique. Application a la synthese d'esters anticholinergiques du quinuclidinol-3

Enantiomeric 2-(3-thienyl)-2-cyclohexyl-2-hydroxy acetic acids 1 were obtained by the resolution of (+/-)-1 using (+)- and (-)-ephedrine as the resolving agents, and by asymmetric synthesis; (+)-1 was assigned S absolute configuration (i) by comparing the circular dichroism spectra of a series of derivatives of 1 with those of the corresponding derivatives of S-(+)-2-phenyl-2-cyclohexyl-2-hydroxy acetic acid 1', and (ii) by application of the quasi-racemate method.On transesterification of the methyl esters of 1, R-(+)-2 and S-(-)-2, with R-(-)- or S-(+)-1-azabicyclo-3-octanol (or 3-quinuclidinol), the four diastereoisomers of 3-quinuclidinyl 2-(3-thienyl)-2-cyclohexyl-2-hydroxy-acetate were obtained, i.e., (+)-2R, 3'S-6, (-)-2S, 3'R-6, (+)-2R, 3'R-7, and (-)-2S, 3'S-7.These compounds exhibited anticholinergic activity.