58794-05-1 Usage
General Description
α-Methyl-3-isoquinolinemethanol, also known as Mecamylamine, is a chemical compound that belongs to the class of tertiary amines. It is a noncompetitive antagonist of nicotinic acetylcholine receptors, meaning it blocks the action of acetylcholine at these receptors. Mecamylamine has been studied for its potential use in treating nicotine addiction and has been shown to reduce the reinforcing effects of nicotine. Additionally, it has also been investigated for its potential use in treating certain psychiatric disorders, such as depression and anxiety. However, its use is limited due to its adverse effects, such as dizziness, sedation, and dry mouth, as well as its potential for abuse and dependence.
Check Digit Verification of cas no
The CAS Registry Mumber 58794-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,7,9 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 58794-05:
(7*5)+(6*8)+(5*7)+(4*9)+(3*4)+(2*0)+(1*5)=171
171 % 10 = 1
So 58794-05-1 is a valid CAS Registry Number.
58794-05-1Relevant articles and documents
Homochiral isoquinolines by lipase-catalysed resolution and their diastereoselective functionalisation
Guanti, Giuseppe,Riva, Renata
, p. 1185 - 1200 (2007/10/03)
Kinetic resolution of racemic isoquinoline alcohols and acetates has been successfully accomplished using lipases as chiral catalysts. The diastereoselective functionalisation of the isoquinoline moiety through the addition of C-nucleophiles to O-protected alcohol 9a in the presence of phenyl chloroformate has been carried out and dihydroquinolyl alcohol derivatives with high diastereomeric excess have been prepared.
