590371-95-2 Usage
General Description
2-Bromo-3-(trifluoromethyl)quinoline is a chemical compound with the molecular formula C10H5BrF3N. It falls under the category of organofluorines, specifically, those that include a quinoline functional group. Quinolines are aromatic compounds with two fused rings (a benzene ring and a pyridine ring). The 2-bromo-3-(trifluoromethyl)quinoline compound includes a bromine atom and a trifluoromethyl group, providing unique properties. 2-broMo-3-(trifluoroMethyl)quinoline has potential applications in medicinal chemistry as several quinoline derivatives demonstrate a range of biological activities including antimalarial, antibacterial, antifungal, anticancer, anti-inflammatory, and analgesic properties. However, the specific properties and uses of 2-Bromo-3-(trifluoromethyl)quinoline have yet to be fully explored. The compound is usually stored in a cool, dry place for optimal preservation.
Check Digit Verification of cas no
The CAS Registry Mumber 590371-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,0,3,7 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 590371-95:
(8*5)+(7*9)+(6*0)+(5*3)+(4*7)+(3*1)+(2*9)+(1*5)=172
172 % 10 = 2
So 590371-95-2 is a valid CAS Registry Number.
InChI:InChI=1S/C10H5BrF3N/c11-9-7(10(12,13)14)5-6-3-1-2-4-8(6)15-9/h1-5H
590371-95-2Relevant articles and documents
Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids
Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred
, p. 1559 - 1568 (2007/10/03)
As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
