593-54-4

Basic information

• Product Name: Methylphosphin
• Synonyms: Methylphosphin;methylphosphane
• CAS NO: 593-54-4
• Molecular Formula: CH₅P
• Molecular Weight: 48.024161
• Mol File: 593-54-4.mol
• Article Data: 20

Chemical Properties

• Boiling Point: -16°C
• Appearance: /
• Vapor Pressure: 2810mmHg at 25°C
• CAS DataBase Reference: Methylphosphin(CAS DataBase Reference)
• NIST Chemistry Reference: Methylphosphin(593-54-4)
• EPA Substance Registry System: Methylphosphin(593-54-4)

Safety Data

• Hazardous Substances Data: 593-54-4(Hazardous Substances Data)

Usage

General Description

Methylphosphin, also known as trimethylphosphine, is a colorless, flammable gas with a pungent odor. It is highly toxic and can cause irritation to the respiratory system and skin upon contact. Methylphosphin is primarily used as a chemical intermediate in the production of agricultural chemicals, pharmaceuticals, and flame retardants. It is also used as a catalyst in various chemical reactions and as a reagent in organic synthesis. Due to its toxic and flammable nature, methylphosphin should be handled with caution and appropriate safety measures.

InChI:InChI=1/CH5P/c1-2/h2H2,1H3

Upstream product

• 74-87-3 methylene chloride 
• 67-66-3 chloroform 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 3167-63-3 diethyl chloromethylphosphonate 
• 7803-51-2 phosphan 
• 65747-63-9 CH₂[P(O)(Me)(OPr-i)]2 
• 4206-94-4 methylphosphinic acid 
• 10419-85-9 diphenyl (chloromethyl)phosphonate 
• 91166-48-2 benzoylmethylphosphine 
• 94477-96-0 methylenebis(methylphosphinic chloride) 
• 41948-89-4 Dimethyl-<α-(ethoxy)-ethyliden>-ammonium-Ion 
• 41948-92-9 5-ethoxy-1-methyl-3,4-dihydro-2H-pyrrolium; tetrafluoroborate 
• 52713-97-0 2-methyl-5-phenyl-2H-1,2,4,3-triazaphosphole 

Downstream Products

• 993-13-5 methylphosphonic acid 
• 1776-86-9 2-Methylphosphino-ethanol 
• 19792-48-4 Methyldiacetatophosphid 
• 5573-52-4 Bis-diethylamino-(methyl-phosphino)-methyl-silan 
• 10103-00-1 (2-Chloro-1,1,3,3-tetrafluoro-allyl)-methyl-phosphane 
• 54772-60-0 1-[Methyl-(2-phosphanyl-ethyl)-phosphanyl]-2-phosphanyl-ethane 
• 5573-48-8 Bis--methyl-phosphin 
• 5573-53-5 Diaethylamino-dimethyl--silan 
• 5573-54-6 Bis--methyl-phosphin 
• 5573-50-2 Bis--methyl-phosphin 
• 67373-54-0 [Dimethyl-(1,1,2-trimethyl-propyl)-silanyl]-methyl-phosphane 
• 67373-55-1 1,1,2,3,3-Pentamethyl-1,3-bis-(1,1,2-trimethyl-propyl)-disilaphosphane 
• 63578-31-4 1,1,7,7-tetra(dimethylamino)-4-methyl-1,4,7-phospha-heptane 
• 75877-14-4 1,2,2,3,3,4,4,5,5-Nonamethyl-[1,2,3,4,5]phosphatetrasilolane 

Relevant articles and documents

Gas-Phase Chemistry of H2P(-)

The gas-phase ion-molecule chemistry of H2P(-) has been investigated by using the flowing afterglow technique.Generated by proton abstraction from PH3 by H2N(-) or OH(-), H2P(-) reacts with N2O, CO2, OCS, CS2, O2, NO2, SO2, CH3X, and (CH3)3SiCl to yield a variety of ion products.Products usually arise from initial nucleophilic attack of H2P(-) on the neutral, followed by intramolecular proton transfer and/or expulsion of a neutral fragment.Many of the reactions are similar to those for H2N(-), though differences are attributable to the weaker nucleophilicity of H2P(-).Product branching ratios and reaction rate constants are reported, and possible mechanistic pathways are discussed.

ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES

A compound of formula (I) for use in the prevention or treatment of a bacterial infection wherein: PX is selected from the group consisting of (P1), (P2) and (P3).

The Ever-surprising chemistry of boron: Enhanced acidity of phosphine·boranes

The gas-phase acidity of a series of phosphines and their corresponding phosphine·borane derivatives was measured by FT-ICR techniques. BH 3 attachment leads to a substantial increase of the intrinsic acidity of the system (from 80 to 110 kJ mol-1). This acidity-enhancing effect of BH3 is enormous, between 13 and 18 orders of magnitude in terms of ionization constants. This indicates that the enhancement of the acidity of protic acids by Lewis acids usually observed in solution also occurs in the gas phase. High- level DFT calculations reveal that this acidity enhancement is essentially due to stronger stabilization of the anion with respect to the neutral species on BH3 association, due to a stronger electron donor ability of P in the anion and better dispersion of the negative charge in the system when the BH3 group is present. Our study also shows that deprotonation of ClCH2PH2 and ClCH 2PH2·BH3 is followed by chloride departure. For the latter compound deprotonation at the BH3 group is found to be more favorable than PH2 deprotonation, and the subsequent loss of Cl- is kinetically favored with respect to loss of Cl - in a typical SN2 process. Hence, ClCH2PH 2·BH3 is the only phosphine·borane adduct included in this study which behaves as a boron acid rather than as a phosphorus acid.

B(C6F5)3-catalyzed silylation versus reduction of phosphonic and phosphinic esters with hydrosilanes

HSiR3/cat-B(C6F)3 induced dealkylation or reduction of esters of phosphorus at 20°C. A specific conversion to silylesters occurred by reaction with tertiary silanes. In contrast, free phosphines were observed in the reaction with mono- or disubstituted silanes. A mechanism was proposed to rationalize these results.