593283-25-1

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, hydrazide
• CAS NO: 593283-25-1
• Molecular Formula: C12H13ClN4O2
• Molecular Weight: 280.714
• Mol File: 593283-25-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, hydrazide(593283-25-1)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, hydrazide(593283-25-1)

Safety Data

• Hazardous Substances Data: 593283-25-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 5948-71-0 4-(4-chlorophenyl)-5-(ethoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one 

Downstream Products

• 1083098-31-0 C₁₄H₁₄ClN₅O₂ 
• 593283-33-1 4-(4-chloro-phenyl)-5-[5-(4-dimethylamino-phenyl)-4H-[1,2,4]triazol-3-yl]-6-methyl-3,4-dihydro-1H-pyrimidin-2-one 
• 593283-31-9 4-(4-chloro-phenyl)-6-methyl-5-[5-(3-nitro-phenyl)-4H-[1,2,4]triazol-3-yl]-3,4-dihydro-1H-pyrimidin-2-one 
• 593283-32-0 4-(4-chloro-phenyl)-5-[5-(4-chloro-phenyl)-4H-[1,2,4]triazol-3-yl]-6-methyl-3,4-dihydro-1H-pyrimidin-2-one 

Relevant articles and documents

Microwave assisted synthesis and characterization of some new annulated pyrimidinone derivatives

4-Aryl-6-methyl-2-pyrimidinone-5-carbohydrazide derivatives have been synthesized from the reaction of different dihydropyrimidinone with hydrazine hydrate. These compounds upon microwave irradiation undergo clean and facile cyclization with chloroacetamide, chloroacetyl chloride and triethylorthoformate and led to the formation of 3-(6-methyl-2-oxo-4-substituted phenyl-1,2,3,4-tetrahydropyrimidin-5-yl)-1,6-dihydro-1,2,4-triazin-5(2H)-one, 4-(6-methyl-2-oxo-4-substitutedphenyl-1,2,3,4-tetrahydropyrimidin-5-yl) tetrahydropyridazine-3,6-dione, 6-methyl-5-(5-oxo-4,5-dihydro-1H-pyrazol-4-yl)- 4-substitutedphenyl-3,4-dihydropyrimidin-2(1H)-one and their substituted derivatives respectively, in quantitative yield. Structures of these newly synthesized compounds were established on the basis of spectra and analytical data.