59445-83-9 Usage
Explanation
The compound's full name, which describes its structure and composition.
Explanation
It is derived from the parent compound, 1-(3-Thienyl)ethanone, by the addition of an oxime group.
Explanation
It serves as a reactant in the preparation of other organic compounds and as a reagent in the synthesis of drugs and pharmaceuticals.
Explanation
It is used in the field of medicinal chemistry, acts as a building block for complex organic molecules, and has potential use in research and development due to its unique chemical properties.
Explanation
The compound's diverse applications in various scientific and industrial fields make it a valuable asset in chemical research and synthesis.
Explanation
The presence of a thiophene ring and an oxime group in its molecular structure contributes to its unique chemical properties and reactivity.
Explanation
The chemical formula represents the compound's composition, consisting of carbon (C), hydrogen (H), nitrogen (N), oxygen (O), and sulfur (S) atoms.
Explanation
The molecular weight is the sum of the atomic weights of all atoms in the molecule, which is around 139.20 grams per mole for 1-(3-Thienyl)ethanone oxime.
Explanation
Based on its molecular weight and structure, it is expected to be a solid or liquid at room temperature, although specific information on its physical state is not provided.
Explanation
The material does not provide information on the compound's solubility in various solvents, which would depend on its polarity and molecular interactions.
Type
Oxime derivative
Functionality
Reactant and Reagent
Applications
Medicinal Chemistry, Organic Synthesis, and Research & Development
Versatility
Wide range of potential applications
Structure
Contains a thiophene ring and an oxime group
Molecular Weight
Approximately 139.20 g/mol
Physical State
Likely a solid or liquid at room temperature
Solubility
Solvent compatibility is not specified
Check Digit Verification of cas no
The CAS Registry Mumber 59445-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,4,4 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 59445-83:
(7*5)+(6*9)+(5*4)+(4*4)+(3*5)+(2*8)+(1*3)=159
159 % 10 = 9
So 59445-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H7NOS/c1-5(7-8)6-2-3-9-4-6/h2-4,8H,1H3
59445-83-9Relevant articles and documents
Rhodium(iii)-catalyzed asymmetric [4+1] spiroannulations of: O -pivaloyl oximes with α-diazo compounds
Chang, Junbiao,Deng, Wei-Qiao,Kong, Lingheng,Li, Xingwei,Liu, Bingxian,Sun, Lincong,Wang, Fen,Zhao, Yanlian
supporting information, p. 8268 - 8271 (2021/08/25)
Chiral RhIII catalysts can catalyze the asymmetric [4+1] spiroannulation of O-pivaloyl oximes with α-diazo homophthalimides under redox-neutral and acid/base-neutral conditions, leading to formation of chiral spirocyclic imines as a result of C-H activation and N-O cleavage. The reaction proceeded with high efficiency and features broad substrate scope, mild reaction conditions, and high to excellent enantioselectivities. This journal is
Redox-Neutral Access to Isoquinolinones via Rhodium(III)-Catalyzed Annulations of O-Pivaloyl Oximes with Ketenes
Yang, Xifa,Liu, Song,Yu, Songjie,Kong, Lingheng,Lan, Yu,Li, Xingwei
supporting information, p. 2698 - 2701 (2018/05/22)
A mild and redox-neutral [4 + 2] annulation of O-pivaloyl oximes with ketenes has been realized for synthesis of quaternary-carbon-stereocenter-containing (QCSC) isoquinolinones, where the N-OPiv not only acts as an oxidizing group but also offers coordination saturation to inhibit protonolysis. The reaction mechanism has been studied by DFT calculations.
Copper-catalyzed synthesis of thiazol-2-yl ethers from oxime acetates and xanthates under redox-neutral conditions
Zhu, Zhongzhi,Tang, Xiaodong,Cen, Jinghe,Li, Jianxiao,Wu, Wanqing,Jiang, Huanfeng
supporting information, p. 3767 - 3770 (2018/04/17)
A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been developed. Various oxime acetates, whether derived from aryl ketones or alkyl ketones, or natural product cores are suitable for this conversion. Unique dihydrothiazoles were also obtained when both reaction sites were methine. Mechanistic studies indicated that imino copper(iii) intermediates were involved. In addition, this protocol proceeded under redox-neutral conditions and did not require additives or ligands.
