5957-56-2

Basic information

• Product Name: [4R,(-)]-1,2,3,4,4aα,5,8,8aβ-Octahydro-6-methyl-1-methylene-4-isopropylnaphthalene
• Synonyms: [4R,(-)]-1,2,3,4,4aα,5,8,8aβ-Octahydro-6-methyl-1-methylene-4-isopropylnaphthalene;3,10(15)-Cadinadiene;γ2-Cadinene
• CAS NO: 5957-56-2
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.35106
• Mol File: 5957-56-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [4R,(-)]-1,2,3,4,4aα,5,8,8aβ-Octahydro-6-methyl-1-methylene-4-isopropylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: [4R,(-)]-1,2,3,4,4aα,5,8,8aβ-Octahydro-6-methyl-1-methylene-4-isopropylnaphthalene(5957-56-2)
• EPA Substance Registry System: [4R,(-)]-1,2,3,4,4aα,5,8,8aβ-Octahydro-6-methyl-1-methylene-4-isopropylnaphthalene(5957-56-2)

Safety Data

• Hazardous Substances Data: 5957-56-2(Hazardous Substances Data)

Upstream product

• 27548-51-2 (4aS,8R,8aR)-8-Isopropyl-5-methylene-octahydro-naphthalen-2-one 
• 917-54-4 methyllithium 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 29292-32-8 (4R,4aR,8aR)-4-Isopropyl-6-methyl-3,4,4a,5,8,8a-hexahydro-2H-naphthalen-1-one 
• 81373-90-2 8-isopropyl-2-mesyloxymethyl-5-methylene-Δ²-decalene 
• 82096-11-5 (4S,4aS,8aS)-4-Isopropyl-6-trimethylsilanylmethyl-3,4,4a,5,8,8a-hexahydro-2H-naphthalen-1-one 
• 27548-51-2 (1R*,5S*,6S*)-(+/-)-5-Isopropyl-2-methylenbicyclo<4.4.0>decan-8-on 
• 81373-89-9 2-hydroxymethyl-8-isopropyl-5-methylene-Δ²-decalene 
• 81373-88-8 2-epoxy-8-isopropyl-5-methylenedecalin 
• 122305-06-0 7-chloro-10-isopropyl-3,7-dimethylbicyclo<4.4.0>dec-3-ene 
• 122305-05-9 trans-3-(4-chloro-2-methyl-2(E)-butenyl)-4-isopropyl-1-methylcyclohex-1-ene 

Downstream Products

• 481-35-6 (+/-)-cadinene dihydrochloride 

Relevant articles and documents

DIASTEREOSELECTIVE SYNTHESIS OF β- AND γ2-MUUROLENE: A CARBOCATIONIC PATHWAY FROM MONO- TO SESQUITERPENES

The Lewis acid catalysed addition of the piperityl chlorides 6 to isoprene yields adduct 7, which undergoes a cis-stereoselective cyclisation to give the diastereoisomeric muurolene monohydrochlorides 8.Treatment with potassium tert-butoxide affords β- an

A New Synthesis of (+/-)-γ2-Cadinene

8-Isopropyl-5-methylene-2-oxo-decalin (II) on nucleophilic epoxidation with dimethyloxosulphonium methylide under nitrogen atmosphere gives the epoxide (III) which undergoes stereoselective cleavage with lithium diisopropylamide to furnish the allylic alcohol, 2-hydroxymethyl-8-isopropyl-5-methyl-Δ2-decalene (IV).Conversion of IV into the corresponding mesylate (V) using mesyl chloride/TEA in dry dichloromethane and subsequent reduction of V with LAH yields (+/-)-γ2-cadinene (I).