59627-41-7Relevant articles and documents
Borylation of propargylic substrates by bimetallic catalysis. Synthesis of allenyl, propargylic, and butadienyl bpin derivatives
Zhao, Tony S. N.,Yang, Yuzhu,Lessing, Timo,Szabó, Kálmán J.
, p. 7563 - 7566 (2014/06/10)
Bimetallic Pd/Cu and Pd/Ag catalytic systems were used for borylation of propargylic alcohol derivatives. The substrate scope includes even terminal alkynes. The reactions proceed stererospecifically with formal S N2′ pathways to give allenyl boronates. Opening of propargyl epoxides leads to 1,2-diborylated butadienes probably via en allenylboronate intermediate.
Stereoselective synthesis of syn-configured α-allenols by rhodium-catalyzed reaction of alkynyl oxiranes with arylboronic acids
Miura, Tomoya,Shimada, Masahiko,De Mendoza, Paula,Deutsch, Carl,Krause, Norbert,Murakami, Masahiro
supporting information; experimental part, p. 6050 - 6054 (2009/12/26)
(Chemical Equation Presented) A rhodium-catalyzed reaction of alkynyl oxiranes with arylboronic acids affords syn-configured α-allenols with high diastereoselectivity. The reaction is initiated by addition of an arylrhodium(I) species onto the alkyne moie
Diastereoselective syn or anti opening of propargylic epoxides. Synthesis of α-allenic alcohols
Alexakis,Marek,Mangeney,Normant
, p. 1677 - 1696 (2007/10/02)
Propargylic epoxides easily react with Grignard reagents and catalytic amounts of copper(I) salt to afford α-allenic alcohols. The reaction is highly diastereoselective and its stereochemical outcome (syn or anti isomer) can be fully controlled. The syn d
