5966-28-9 Usage
Uses
1. Used in Pharmaceutical Applications:
N-OLEOYL-D-SPHINGOSINE is used as a therapeutic agent for the treatment of various conditions, including insulin resistance and obesity. Its elevated levels in overweight and insulin-resistant subjects suggest its potential role in modulating these conditions.
2. Used in Cancer Research and Treatment:
N-OLEOYL-D-SPHINGOSINE is used as a biomarker for advanced ovarian cancer. The increased levels of this ceramide in the plasma and ovarian tissue of patients with advanced ovarian cancer indicate its potential use in diagnosing and monitoring the progression of the disease.
3. Used in Drug Delivery Systems:
Similar to gallotannin, N-OLEOYL-D-SPHINGOSINE can also be employed in the development of novel drug delivery systems to enhance its applications and efficacy against various diseases, including cancer. Organic and metallic nanoparticles can be used as carriers for N-OLEOYL-D-SPHINGOSINE delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 5966-28-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,6 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5966-28:
(6*5)+(5*9)+(4*6)+(3*6)+(2*2)+(1*8)=129
129 % 10 = 9
So 5966-28-9 is a valid CAS Registry Number.
5966-28-9Relevant articles and documents
The synthesis and biological characterization of a ceramide library
Chang, Young-Tae,Choi, Jaehwa,Ding, Sheng,Prieschl, Eva E.,Baumruker, Thomas,Lee, Jae-Mok,Chung, Sung-Kee,Schultz, Peter G.
, p. 1856 - 1857 (2007/10/03)
A facile synthesis of a combinatorial ceramide library and their activities in the NF-κB pathway and in apoptosis induction/prevention were demonstrated. A novel NF-κB activating molecule was discovered among ceramide containing β-galactose, and the structural requirements of ceramides for apoptosis induction was elucidated. Copyright